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This study characterized the crystal structures and supramolecular architectures of new salts made from 2,4-diaminopyrimidine and different dicarboxylic acids, revealing subtle differences in crystal packing and hydrogen-bonding patterns, particularly influenced by sulfur atom interactions, through Hirshfeld analysis and enrichment ratios.

In this study, researchers addressed the limitations of adenosine's practical application in treating inflammation, oxidative stress, and tissue repair due to its poor water solubility and low transdermal permeability. Results are not reported in the abstract.

Made 8 minoxidil samples; 1 cocrystal, 7 salts formed.

In this study, researchers developed a supramolecular hydrogel combining minoxidil and salicylic acid, finding that it accelerates hair growth and enhances hair follicle regeneration in vivo, suggesting its potential as an effective treatment for alopecia.

This study found that the cocrystal of mycophenolic acid with isonicotinamide significantly improved solubility and dissolution rate, while two other cocrystals showed decreased performance in these areas.