research The human skin as a hormone target and an endocrine gland
This review explores the complex endocrine functions of human skin and its role as a peripheral endocrine organ, but reports no new clinical results.
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5 / 1000+ resultsresearch Exploring mechanisms of the Ligusticum chuanxiong Hort. and Angelica sinensis (Oliv.) Diels pair in seborrheic alopecia: An integrated data mining, network pharmacology, and experimental study
In this study, topical application of a combined essential oil from Ligusticum chuanxiong and Angelica sinensis significantly improved hair regrowth in testosterone-induced alopecia in mice, potentially by modulating steroid hormone-related proteins.
research Sesamin alleviates androgenetic alopecia by targeting the AR MAPK Wnt axis
In this study, researchers found that sesamin, a component of sesamum, modulated the AR-MAPK-Wnt signaling pathway in DHT-stimulated HaCaT keratinocytes, demonstrating potential multi-target activity against molecular events in androgenetic alopecia.
research Nutrition of women with hair loss problem during the period of menopause
This review discusses the role of diet in managing hair loss during menopause and reports no new clinical results; it highlights the importance of nutrients like sulfur amino acids, vitamins, and minerals.
research Emerging Roles of Steroid-binding Globulins
This abstract lists key topics related to non-genomic steroid effects and protein interactions, but reports no new research findings.
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5 / 580 resultscommunity Why do we have head hair in first place if we evolved to start losing it in some cases as soon as puberty hits
Hair loss is influenced by genetics and sensitivity to hormones like DHT. Treatments like Minoxidil and finasteride are commonly used, and baldness persists as it doesn't affect reproductive success.
community Sometimes the hair loss was in our control the whole time
The conversation discusses hair loss and the potential impact of diet and lifestyle changes, particularly increased protein intake, on hair health. The original poster shared their experience of improved hair appearance after weight loss and dietary changes, despite skepticism from others about lighting differences in photos and the effectiveness of diet alone without finasteride or minoxidil.
community Creatine Doesn’t Cause Hair Loss: Stop the BS
Creatine does not cause hair loss, despite many users reporting personal experiences of hair shedding. Scientific evidence shows no link between creatine and increased hair loss or hormone changes.
community 5 alpha reductase type 1 is in brain tissue producing the main endogenous gabaergic allopregnanolone, not 2. How can finasteride as a 5ar2 lower that?
Finasteride and dutasteride are discussed for hair loss, with concerns about their effects on neurosteroids and potential side effects like depression. Alternatives like topical estrogen and lifestyle changes are considered, with varying opinions on mental health and hair regrowth.
community Minoxidil is a 5ar inhibitor according to research
Minoxidil may inhibit androgen receptors and affect hormonal pathways, potentially explaining its effectiveness in treating androgenetic alopecia (AGA). Users discuss its varying effectiveness on scalp versus facial hair and note fewer side effects with topical use compared to oral.
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