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research Efficacy of a Hair Tonic Containing Human Umbilical Cord Blood Mesenchymal Stem Cell-derived Conditioned Media in Patients with Androgenetic Alopecia

January 2019 in “Journal of Clinical Dermatology”

This study found that a hair tonic containing a human umbilical cord blood mesenchymal stem cell-derived conditioned medium significantly increased hair density, thickness, and growth rate in patients with androgenetic alopecia.

research THE EFFECT OF HAIR TONIC FROM SECRETOME MESENCHYMAL STEM CELL ON HAIR GROWTH IN HAIR LOSS CASES

January 2026 in “International Journal of Applied Pharmaceutics”

This study found that a hair tonic containing 10% mesenchymal stem cell secretome significantly increased hair density in volunteers with alopecia after eight weeks, suggesting its potential as an effective treatment option for hair growth stimulation.

research Topical RT1640 treatment effectively reverses gray hair and stem cell loss in a mouse model of radiation‐induced canities

7 citations , July 2020 in “Pigment cell & melanoma research”

In this study, RT1640 was found to promote hair pigment system regeneration and expand melanocyte stem cell pools in a mouse model, suggesting potential applications for aging-related hair disorders.

research Human epithelial stem cell survival within their niche requires “tonic” cannabinoid receptor 1‐signalling—Lessons from the hair follicle

14 citations , February 2021 in “Experimental Dermatology”

This study found that activating CB1 receptor signaling in human hair follicles increased stem cell proliferation while reducing differentiated cell survival, suggesting CB1's role as a survival stimulus for epithelial stem cells.

research Efficacy of a Hair Tonic Containing Human Umbilical Cord Blood Mesenchymal Stem Cell-derived Conditioned Media in Patients with Androgenetic Alopecia

January 2019 in “대한피부과학회지”

In this study, a hair tonic containing human umbilical cord blood mesenchymal stem cell-derived conditioned medium significantly increased hair density, thickness, and growth rate in patients with androgenetic alopecia.

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Learn

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learn Stem Cell Factor

Can stem cell factor be combined with other topical hair loss solutions? No published human trial has tested topical stem cell factor alongside minoxidil or other established treatments, so neither the safety nor the benefit of the combination has been established. Community users report layering these products, but that is anecdote rather than clinical evidence.
Does stem cell factor help activate dormant hair follicles? Lab and mouse studies link stem cell factor to hair colour; it has not been shown to reactivate dormant hair follicles in people.
What is stem cell factor and why is it used in hair growth treatments? Stem cell factor is a signalling protein linked to hair colour in lab and mouse studies; it is not a proven hair-loss treatment in people.
All 4 questions on Stem Cell Factor →

learn PP405

mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials

learn Procyanidin

Plant polyphenol found in apples and grape seeds

learn Hair Transplant

Can a hair transplant be combined with other treatments? Clinics commonly say a transplant is combined with other treatments, most often minoxidil, finasteride or PRP, but the evidence behind each add-on differs. Some of the add-ons offered, such as stem-cell or exosome products, are not approved treatments for hair loss.

learn Hair Multiplication

extract, clone, and reinsert your own hair cells

learn SCUBE3

Signalling protein made in the hair follicle

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Community Join

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community Calecim (PTT-6) Advanced Hair System with Topical Exosomes and Growth Factors for Hair Growth

2 years ago

Calecim (PTT-6) Advanced Hair System is a 6-week hair restoration product using stem cell-derived ingredients to stimulate hair growth. Users are skeptical, calling it overpriced and ineffective, suggesting alternatives like LLLT devices or PRP treatments.

community New growth, not sure from which treatment(stem cells or RU58841), hair line extending!

4 upvotes 11 months ago

The user experienced new hair growth after switching from oral finasteride to topical RU58841 with minoxidil and undergoing stem cell therapy. They noticed new hairs at the hairline and temples, but are unsure which treatment is responsible.

community PRP / laser / stem cell treatment before or after hair transplant – worth it?

1 upvotes 1 month ago

The user is considering whether to undergo additional treatments like PRP, low-level laser therapy, and stem cell treatment before or after a planned hair transplant, while already using minoxidil and starting finasteride. They are unsure if these treatments are worth the significant cost and are seeking advice from others who have had similar experiences.

community Any promising new research or techniques for hair loss treatment and hair transplants?

in Research/Science 6 upvotes 1 year ago

The conversation discusses new hair loss treatments like stem cell therapy, exosome treatments, and DHI, with mentions of GT20029, Amp303, and Plated PRP Serum as promising options. It also notes the use of dutasteride, topical finasteride, and minoxidil, but the focus is on non-hormonal innovations.

community First post: Baby Hair Regrowing on temples at 39

11 upvotes 11 months ago

A 39-year-old experienced hair regrowth on his temples after switching from finasteride to topical RU58841 combined with 5% minoxidil. He also underwent stem cell treatment and noticed improvements, attributing the regrowth mainly to the change in treatment.

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