research Treatment of Hirsutism With Spironolactone
This study reported that spironolactone at 200 mg/day significantly improved facial hair growth in women with hirsutism and showed a sustained reduction in ovarian androgens over one year.
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5 / 1000+ resultsresearch Comparison of flutamide and spironolactone in the treatment of hirsutism: a randomized controlled trial
This study found that flutamide was more effective than spironolactone in reducing symptoms of hirsutism and related conditions in premenopausal women, with fewer discontinuations due to side effects.
research The effects of two doses of spironolactone on serum androgens and anagen hair in hirsute women
This study found that spironolactone reduced serum androstenedione and anagen hair shaft diameter in hirsute patients but did not significantly alter unbound testosterone levels, suggesting its effects are primarily peripheral.
research A Novel Use of Spironolactone: Treatment of Hirsutism
This study found that spironolactone significantly reduced hair growth in hirsute women, with noticeable effects in 3-5 months, and decreased serum testosterone levels in all participants.
research Oral Spironolactone for Acne Vulgaris in Adult Females: A Hybrid Systematic Review
This systematic review concluded that the support for using spironolactone at commonly prescribed doses is based on evidence of limited quality.
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5 / 848 resultscommunity Spironolactone vs finasteride - advice for female with AGA
Spironolactone and finasteride are not recommended for women planning pregnancy due to birth defect risks. Both need to be stopped months before conception, and finasteride is generally not advised for women.
community Does the effect of spironolactone on androgenetic alopecia really weaken over time?
Spironolactone can remain effective for a long time in treating androgenetic alopecia, but it may not completely stop hair loss. Hair loss treatments like spironolactone, finasteride, and dutasteride slow down hair loss rather than cure it, and their effectiveness can vary based on individual response and the aggressiveness of the condition.
community Will the hair that has thinned due to AGA become thicker from taking spironolactone?
Spironolactone may help reverse hair miniaturization in AGA. Combining it with minoxidil can promote thicker hair.
community Low dose spiro with 5ARI inhibitor
Spironolactone, finasteride, and dutasteride are discussed for hair maintenance, with concerns about testosterone and side effects like gynecomastia. Spironolactone is noted for use in both bodybuilding and hormone therapy, with low doses considered for minimizing side effects.
community Spironolactone VS dutasteride for female pattern hair loss
Spironolactone is more potent and lowers testosterone and DHT, while dutasteride only impacts DHT. For female hair loss, checking hormones and considering treatments like oral minoxidil, spironolactone, or topical minoxidil is recommended.
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5 / 12 results- How does spironolactone help reduce hair loss when used in topical or oral treatments? Spironolactone is thought to slow androgen-driven follicle miniaturisation by blocking androgen receptors; the trials are small, mostly in women and mostly alongside minoxidil. It is a prescription drug and its use for hair loss is off-label.
- Is spironolactone better for hair regrowth as a pill or as a scalp solution? Oral spironolactone has the stronger published evidence for hair regrowth; topical versions cause fewer systemic side effects but have been studied far less, and no trial has compared the two head to head.
- Who is spironolactone used for in androgen-related hair thinning, and who should avoid it? Studies of spironolactone for hair loss are mostly in adult women; its use is off-label, it is avoided in pregnancy and generally not used in men, and the US label advises potassium checks (DailyMed, Aldactone).
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