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GlossaryNasolabial Folds (Smile Lines)

skin creases running from nose sides to mouth corners

Nasolabial folds, also known as smile lines or laugh lines, are the skin creases that run from each side of the nose to the corners of the mouth. These folds become more prominent with age due to the loss of skin elasticity, fat, and collagen, and are a common focus in cosmetic treatments aimed at reducing the appearance of aging.

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research A Single Intradermal Injection of Autologous Adipose-Derived Stem Cells Rejuvenates Aged Skin and Sharpens Double Eyelids

July 2023 in “Journal of personalized medicine”

Injecting a person's own fat stem cells into their skin can make it look younger and improve double eyelids for over a year.

research Differences in Perceptions of Beauty and Cosmetic Procedures in Ethnic Patients

49 citations , June 2009 in “Seminars in Cutaneous Medicine and Surgery”

The cosmetic industry should adapt to the varied beauty standards of ethnic groups and offer specialized treatments.

research The Aging Face

22 citations , September 2018 in “Medical Clinics of North America”

Facial aging is caused by natural processes and external factors, and can be managed with preventative measures and a variety of treatments tailored to individual needs.

research The Facelift

7 citations , August 1989 in “The Journal of Dermatologic Surgery and Oncology”

Facelifts can lead to high patient satisfaction and a quick recovery when done correctly.

research Skin and Hair Changes After Forty

April 2014 in “Journal of evolution of medical and dental sciences”

Women over forty can maintain skin and hair health with lifestyle and dietary changes.

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community Deep wrinkles in last year since starting oral minoxidil? Anyone else?

in Minoxidil 10 upvotes 1 year ago

A user noticed deeper facial wrinkles since starting oral minoxidil in February 2023 and is concerned about its effects on collagen production. Other factors include past accutane use, high stress, poor sleep, and COVID-19.

community Same haircut two years apart. Just Minoxidil for the first 8 months and then added Finasteride as well. Not a dramatic change but an improvement I think.

in Progress Pictures 202 upvotes 2 months ago

The user shared progress pictures showing hair improvement after using Minoxidil for eight months and then adding Finasteride, noting no dramatic change but some improvement. The user experienced a shed after starting Minoxidil but not after adding Finasteride, and reported no side effects from Finasteride.

community Wrinkly under eyes at 24?! Possible Minoxidil side effect?

in Minoxidil 17 upvotes 4 years ago

A user noticed wrinkling under one eye, possibly due to Minoxidil use. They seek advice on preventing or fixing this issue.

community Haircafe - TOPICAL minoxidil is an anti aging drug

in Minoxidil 249 upvotes 8 months ago

Topical minoxidil may cause skin aging effects like wrinkles and dark circles, possibly due to its alcohol content, while oral finasteride is reported to make users look younger. Switching to oral minoxidil or using moisturizers might help reduce these skin issues.

community My microneedling journey (no min, fin, etc)

in Microneedling 210 upvotes 11 months ago

The user experienced positive hair growth results using microneedling with rosemary and mint oil, without Minoxidil, Finasteride, or RU58841. They switched from a dermaroller to a microneedling pen and targeted different scalp areas weekly.

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