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GlossaryNasolabial Folds (Smile Lines)

skin creases running from nose sides to mouth corners

Nasolabial folds, also known as smile lines or laugh lines, are the skin creases that run from each side of the nose to the corners of the mouth. These folds become more prominent with age due to the loss of skin elasticity, fat, and collagen, and are a common focus in cosmetic treatments aimed at reducing the appearance of aging.

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research A Single Intradermal Injection of Autologous Adipose-Derived Stem Cells Rejuvenates Aged Skin and Sharpens Double Eyelids

July 2023 in “Journal of personalized medicine”

Injecting a person's own fat stem cells into their skin can make it look younger and improve double eyelids for over a year.

research Differences in Perceptions of Beauty and Cosmetic Procedures in Ethnic Patients

49 citations, June 2009 in “Seminars in Cutaneous Medicine and Surgery”

The cosmetic industry should adapt to the varied beauty standards of ethnic groups and offer specialized treatments.

research The Aging Face

22 citations, September 2018 in “Medical Clinics of North America”

Facial aging is caused by natural processes and external factors, and can be managed with preventative measures and a variety of treatments tailored to individual needs.

research The Facelift

7 citations, August 1989 in “The Journal of Dermatologic Surgery and Oncology”

Facelifts can lead to high patient satisfaction and a quick recovery when done correctly.

research Skin and Hair Changes After Forty

April 2014 in “Journal of evolution of medical and dental sciences”

Women over forty can maintain skin and hair health with lifestyle and dietary changes.

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community Deep wrinkles in last year since starting oral minoxidil? Anyone else?

in Minoxidil 10 upvotes 6 months ago

A user noticed deeper facial wrinkles since starting oral minoxidil in February 2023 and is concerned about its effects on collagen production. Other factors include past accutane use, high stress, poor sleep, and COVID-19.

community Wrinkly under eyes at 24?! Possible Minoxidil side effect?

in Minoxidil 19 upvotes 3 years ago

A user noticed wrinkling under one eye, possibly due to Minoxidil use. They seek advice on preventing or fixing this issue.

community My microneedling journey (no min, fin, etc)

in Microneedling 197 upvotes 1 month ago

The user experienced positive hair growth results using microneedling with rosemary and mint oil, without Minoxidil, Finasteride, or RU58841. They switched from a dermaroller to a microneedling pen and targeted different scalp areas weekly.

community My Hair Loss Journey and Warnings About Finasteride

in Finasteride/Dutasteride 9 upvotes 1 year ago

User experienced hair loss and tried Minoxidil, laser helmet, and Finasteride. Finasteride caused depression and sexual side effects, but user had a successful hair transplant.

community [26M] 3.5 year update. Fin+Min

in Progress Pictures 3399 upvotes 5 months ago

A user shared their 3.5-year hair loss treatment journey using finasteride and minoxidil, showing significant hair density improvement and no noticeable side effects. The user also mentioned the confidence boost from shaving their head and the positive impact of the treatments.

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