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Androgen Receptor Activation Integrates Complex Transcriptional Effects in Osteoblasts, Involving the Growth Factors TGF-β and IGF-I, and Transcription Factor C/EBPδ

research Androgen Receptor Activation Integrates Complex Transcriptional Effects in Osteoblasts, Involving the Growth Factors TGF-β and IGF-I, and Transcription Factor C/EBPδ

11 citations, July 2015 in “Gene”

DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.

research Tsc2 Disruption in Mesenchymal Progenitors Regulates Hair Follicles and TGF Beta Signaling

April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology”

Disrupting the Tsc2 gene in certain cells leads to thicker skin, larger hair, and changes in hair growth signaling, which can be partly reversed with specific treatment.

research A Role for the TGF-β/BMP Co-Receptor Endoglin in the Molecular Oscillator That Regulates the Hair Follicle Cycle

26 citations, September 2018 in “Journal of Molecular Cell Biology”

Endoglin is crucial for proper hair growth cycles and stem cell activation in mice.

research Live Imaging of Smad2/3 Signaling in Mouse Skin Wound Healing

12 citations, September 2007 in “Wound repair and regeneration”

Smad2/3-dependent TGF-β signaling increases during wound healing.

research A Role for the TGF-β/BMP Co-Receptor Endoglin in the Molecular Oscillator That Regulates the Hair Follicle Cycle

December 2017 in “bioRxiv (Cold Spring Harbor Laboratory)”

Endoglin is important for proper hair growth cycles and stem cell activation in hair follicles.

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community Creatine's effect on Hair Loss and DHT

in Research/Science 102 upvotes 9 months ago

A 21-year-old male managed to control his hair loss using Nizoral, RU58841, and finasteride, but experienced increased scalp itchiness after starting creatine, which subsided upon stopping creatine. Users shared mixed experiences on whether creatine affects hair loss, with some reporting negative effects and others seeing no change or defending its benefits.

community 2.5 months topical minoxidil Progress

in Progress Pictures 440 upvotes 10 months ago

The conversation is about a user's hair regrowth after 2.5 months using topical minoxidil. Some suggest adding finasteride for long-term results, while others share their experiences with side effects or alternative treatments like dermarolling and dietary improvements.

community Progress – 24.03.21 – 29.06.22 Finasteride 1mg a day

in Progress Pictures 1075 upvotes 2 years ago

A user's progress with treating hair loss using 1mg finasteride per day, with reports of no noticeable side effects and positive results. Other users have shared their experiences with different treatments, such as Dutasteride and Minoxidil.

community Finasteride only reduces scalp DHT by ~40%. Why does it work?

in Finasteride/Dutasteride 37 upvotes 1 year ago

How Finasteride and Dutasteride help reduce hair loss by reducing the amount of DHT in scalp areas, as well as discussing factors such as sensitivity to DHT, 5α-reductase expression in different parts of the hair follicle, and scalp tension.

community Minox and fin since start of January 2020, also shaved my head twice since then to get full effects of the minoxidil and reach the whole scalp easier, that’s honestly a huge key

in Progress Pictures 234 upvotes 3 years ago

User experienced significant hair regrowth using Minoxidil and Finasteride since January 2020, with no side effects reported. Shaving head twice helped Minoxidil reach scalp more effectively.

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