11 citations
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January 2013 in “Journal of the Saudi Society of Dermatology & Dermatologic Surgery”
This study found that applying silymarin gel topically on rat wounds improved fibroblast proliferation, collagen formation, and wound closure more than a gel-base alone or no treatment.
November 2023 in “The journal of investigative dermatology/Journal of investigative dermatology”
This study reported that adipose stem cell exosomes, combined with microneedling, improved facial skin wrinkles, elasticity, hydration, and pigmentation compared to a placebo, with significant results on the Global Aesthetic Improvement Scale and no serious adverse events noted in treated individuals.
4 citations
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October 2022 in “Frontiers in public health”
In this study on C57BL/6 mice, researchers found that cadmium chloride exposure led to metabolic disruption, accelerated skin aging, and impaired hair regeneration, with more severe effects observed at higher doses.
4 citations
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January 2005 in “Indian Journal of Animal Research”
This study describes the structural composition of the skin's dermis in experimental animals, highlighting the arrangement of collagen, elastic, and reticular fibers as well as associated glands and muscles.
The user has been using liposomal topical finasteride since late 2022, progressively increasing the dose, but DHT serum levels remain largely unchanged. Despite using finasteride, minoxidil, microneedling, and ketoconazole, hair condition has neither improved nor worsened.
Finasteride is prescribed at 1mg because it is FDA-approved and proven effective, despite evidence that 0.2mg may similarly reduce DHT. The 1mg dose is more effective for hair growth, and lower doses are less available.
Microneedling for hair loss, with concerns about potential scarring and hair breakage. Recommendations include using 0.5-0.8mm needles, opting for dermastamps or pens, and limiting frequency to twice a month.
Topical Metformin shows potential for regenerating hair follicles and minimizing scarring in hair transplant donor areas, similar to Verteporfin but without its side effects. The discussion suggests considering Metformin for post-hair transplant care, though more human trials are needed.
Low doses of dutasteride are as effective as higher doses for hair regrowth, with fewer side effects. Users find success taking it 2-3 times a week instead of daily.