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research Skin Organ Culture: Why?

22 citations , April 1987 in “International Journal of Dermatology”

Skin organ culture helps us understand skin biology and diseases better.

A Model System for Long-Term Serum-Free Suspension Organ Culture of Human Fetal Tissues: Experiments on Digits and Skin from Multiple Body Regions

research A model system for long-term serum-free suspension organ culture of human fetal tissues: experiments on digits and skin from multiple body regions

17 citations , January 1997 in “Cell and Tissue Research”

This study found that a serum-free DMEM-F12 medium with 45% oxygen best supports in vitro development and differentiation of human fetal skin, closely mimicking the in vivo state.

research Reorganization of hair follicles in human skin organ culture induced by cultured human follicle-derived cells

56 citations , July 2005 in “Experimental Dermatology”

This study demonstrated that hair follicle-derived cells can induce hair follicle formation in an in vitro skin organ culture system using human retroauricular skin specimens.

research 1350 Human scalp skin as an abundant and accessible source for eccrine sweat gland isolation and organ culture

April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study describes a new method for isolating intact human eccrine glands from scalp follicular units, potentially advancing research on sweat gland physiology.

research Erlotinib-Induced Skin Inflammation Is IL-1 Mediated in KC-Tie2 Mice and Human Skin Organ Culture

15 citations , October 2014 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study suggests that erlotinib exacerbates inflammation in a mouse model of skin disease and that IL-1 inhibition could mitigate skin-related side effects of EGFR inhibitors.

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community So does oral minoxidil age your skin or not

43 upvotes 2 years ago

Oral minoxidil may cause dry skin and dark eye bags but doesn't significantly age the skin. Topical minoxidil is toxic to cats, and some users prefer finasteride.

community Why isn’t anyone talking about this?

29 upvotes 2 years ago

Hair cloning is being developed by companies like Kangstem Biotech and Stemson, with potential availability in a few years. Initial costs are expected to be high, but prices may decrease over time.

community Hair follicle cloning is already possible

in Chat 38 upvotes 1 year ago

Hair follicle cloning is claimed to be possible but not widely available due to potential safety issues, such as cancer risks. Current treatments like finasteride and dutasteride are not effective for everyone, and there is frustration over limited access to these medications.

community So we have 20k dollars human like machines available but no new effective treatment for hairloss since finasteride :)

in Chat 237 upvotes 1 year ago

There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.

community Why do we have head hair in first place if we evolved to start losing it in some cases as soon as puberty hits

140 upvotes 11 months ago

Hair loss is influenced by genetics and sensitivity to hormones like DHT. Treatments like Minoxidil and finasteride are commonly used, and baldness persists as it doesn't affect reproductive success.

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