This research describes mouse models to explore Kindlin-1's role in skin disorders, including Kindler syndrome, revealing novel integrin-independent pathways potentially leading to skin tumors.
This study reported that Indian hedgehog (Ihh) signaling plays a crucial role in regulating tumor progression and metastasis in epithelial cancers, with Ihh deficiency leading to increased malignancy and metastasis in mice.
4 citations
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July 2015 in “Journal of Feline Medicine and Surgery Open Reports”
This case report describes a 10-year-old British Shorthair cat with lethargy, weight loss, alopecia, and spontaneous pruritus, revealing severe skin changes upon examination.
1 citations
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October 2007 in “The Cancer Handbook”
This narrative review discusses models for studying malignant melanoma, basal cell carcinoma, and squamous cell carcinoma, reporting no new experimental findings.
Is scalp micropigmentation suitable for people with sensitive skin?Providers say scalp micropigmentation suits most skin types and describe patch tests, hypoallergenic pigments and a skin consultation for sensitive skin. These are provider claims rather than independent safety evidence, and pigment reactions remain a risk.
The conversation is about concerns over skin aging from using minoxidil for hair loss, with the user planning to use a minimal amount to avoid side effects. Other users suggest that overuse may cause temporary skin dryness but not actual aging, and emphasize proper application.
The conversation discusses the importance of scalp skin barrier health in hair follicle cycling, suggesting treatments like ceramides or niacinamide to support hair growth. It also mentions the use of finasteride for hair loss.
Minoxidil can be effectively delivered through nanoemulsions containing eucalyptol or oleic acid, enhancing its diffusivity and targeting hair follicles. This contradicts the advice against mixing minoxidil with oils in topical formulations.
Collagen supplements for improving skin, hair, nails, and joints. Recommendations include standard collagen peptide powder and Live Conscious collagen peptide, though some users doubt their effectiveness.
Minoxidil is unlikely to cause skin aging at typical doses, and concerns about collagen inhibition are mostly unfounded. Users suggest using sunscreen and tretinoin for skin health, and some combine minoxidil with finasteride for hair maintenance.