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Research

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research Effects of Depilatory Cream Formulation and Contact Time on Mouse Skin

5 citations , March 2023 in “Journal of the American Association for Laboratory Animal Science”

In this study, the researchers observed that both standard body and facial depilatory creams caused significant skin injury in mice, with varying effects depending on the mouse strain and exposure time, although both formulations were effective for hair removal.

research A single center, pilot, double-blinded, randomized, comparative, prospective clinical study to evaluate improvements in the structure and function of facial skin with tazarotene 0.1% cream alone and in combination with GliSODin® Skin Nutrients Advanced A

9 citations , May 2014 in “Clinical Cosmetic and Investigational Dermatology”

This study suggests that combining GliSODin(®) Skin Nutrients with tazarotene cream significantly benefits facial fine wrinkles, photodamage, moisture, and elasticity compared to tazarotene alone.

research Effects of Skin Lightening Cream Agents – Hydroquinone and Kojic Acid, on the Skin of Adult Female Experimental Rats

46 citations , April 2020 in “Clinical Cosmetic and Investigational Dermatology”

This study found that hydroquinone caused structural damage to the skin of rats, while aloe vera reduced this damage, suggesting potential concerns for its use in skin lightening creams.

research Topical Administration of 15‐Deoxy‐Δ^12,14‐Prostaglandin J₂ Using a Nonionic Cream: Effect on UVB‐Induced Skin Oxidative, Inflammatory, and Histopathological Modifications in Mice

9 citations , January 2021 in “Mediators of Inflammation”

In this study, 15d-PGJ2 administered in a topical cream inhibited oxidative and inflammatory skin changes caused by UVB radiation in hairless mice, suggesting it as a promising treatment approach.

research Skin Changes on the Face Caused by Over-the-counter Cosmetic Creams: An Observational Study of Clinical and Dermoscopy Features

January 2023 in “Indian journal of pharmacy practice”

This study observed that dermoscopic features of skin affected by topical corticosteroids and hydroquinone correlated with histopathological changes, highlighting the importance of awareness regarding their long-term adverse effects.

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Community Join

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community how do you get tretinoin for hair? all I get is cream for the skin of the face

in Treatment 1 upvotes 1 year ago

Mixing tretinoin gel with Minoxidil for hair application is discussed, with suggestions to mix per application to avoid clogging and degradation. Some users apply tretinoin cream to the hairline and use Minoxidil and finasteride, noting potential irritation on the crown.

community Does tretinoin cream affect minoxidil absorption if applied first?

in Minoxidil 1 upvotes 11 months ago

Apply tretinoin cream first, then minoxidil, as tretinoin can enhance minoxidil absorption. Allow some time between applications to avoid skin irritation.

community Tretinoin + minoxidil and red-light?

in Minoxidil 2 upvotes 1 year ago

The user has been using minoxidil for over a year with little success, added tretinoin cream, and is considering adding red light therapy. They are advised to use moisturizer to counteract skin sensitivity from tretinoin.

community Can topical Minoxidil use backfire if you’re a non-responder?

1 upvotes 4 months ago

The user has been using finasteride successfully to stop hair shedding and is considering using topical minoxidil for regrowth but is concerned about being a non-responder and potential negative effects. They are cautious about using oral minoxidil due to past heart issues and are exploring other methods like tretinoin cream and dermarolling, though they worry about possible skin damage.

community Putting antihistamine cream on scalp to fight inflammation and itchy scalp?

2 upvotes 3 years ago

Topical antihistamine creams, like diphenhydramine, are being considered for scalp inflammation and itchiness as an adjunct to standard hair loss treatments like minoxidil and finasteride. The user is cautious about oral antihistamines due to potential side effects and is exploring topical options.

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Learn

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learn Rapamycin

Are there any visible side effects when using rapamycin cream or serum on the scalp? Visible side effects may include skin irritation or redness when using rapamycin on the scalp.

learn Hydrocortisone

How do you safely apply hydrocortisone cream or lotion to the scalp without overusing it? The over-the-counter hydrocortisone label sets the limits: a thin film on the affected patch, no more than three or four times a day, and no longer than seven days without a doctor's direction — and the scalp absorbs corticosteroids more than most skin, so prolonged use raises the risk of thinning skin.
Can hydrocortisone be used together with other treatments like minoxidil or steroid injections? Clinicians do use a mild steroid cream to settle the scalp irritation minoxidil can cause, but no verified trial tests hydrocortisone added to minoxidil or to corticosteroid injections, and prolonged scalp use risks skin thinning — combining it is a decision to take with a prescriber.

learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Overview

learn Melatonin

Can melatonin cause side effects on the skin or hair? Melatonin may cause hair loss or thinning in some users, but evidence is limited.

learn Scalp Micropigmentation

Does scalp micropigmentation work on all skin tones and hair colors? Scalp micropigmentation can be customized for various skin tones and hair colors.

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Experts

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SMP Specialist
Noelle Skin
Nice, France

Clinics

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Noelle Skin