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5 / 1000+ resultsresearch Sex- Or Gender-Specific Differences In The Clinical Presentation, Outcome, And Treatment Of SARS-CoV-2
This review highlighted sex and gender differences in the clinical presentation, treatment, and outcomes of COVID-19. Men were found to have a higher risk of severe outcomes, including hospitalization, ICU admission, and mortality, while women were more likely to experience "long COVID" symptoms. Biological factors, such as immune-related genes on the X chromosome and sex hormones, contributed to these disparities. The review emphasized the need for sex-disaggregated analysis in COVID-19 research, as less than 5% of studies had planned for such analysis. It also discussed the influence of sex hormones on immune responses, with testosterone linked to increased severity and estrogen potentially mitigating disease severity. Men exhibited higher levels of inflammatory markers and were more prone to venous thromboembolic events, while women were at greater risk for prolonged symptoms. The document underscored the importance of considering sex-specific factors in COVID-19 treatment and prognosis.
research Improving Translational Research in Sex-Specific Effects of Comorbidities and Risk Factors in Ischemic Heart Disease and Cardioprotection: Position Paper and Recommendations of the ESC Working Group on Cellular Biology of the Heart
The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.
research Molecular Mechanisms Leading to Sex-Specific COVID-19 Prognosis and Targeted Therapies
Men are more at risk for severe COVID-19 due to biological differences, suggesting the need for targeted treatments.
research Sex Differences in Arterial Hypertension
Women may need different blood pressure guidelines than men for heart disease prevention.
research Sex-Specific Difference of Hippocampal Synaptic Plasticity in Response to Sex Neurosteroids
Sex neurosteroids cause different effects on hippocampal synaptic plasticity in males and females.
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5 / 1000+ resultscommunity Why is Finasteride seen as “scary” for men, but hormonal birth control is totally normalized for women?
Finasteride is seen as risky for men due to side effects like erectile dysfunction, while hormonal birth control for women is normalized despite its side effects. The discussion points out a double standard influenced by societal and gender norms.
community Female, 30, PCOS diagnosis, MPB Norwood 2. Endo refuses to give anything other than Spironolactone. Feel like I’m at my wit’s end here.
A 30-year-old female with PCOS and male pattern baldness is frustrated with her endocrinologist's recommendation of only Spironolactone and minoxidil, feeling that dutasteride, finasteride, and progesterone would be more effective. Other users suggest various online sources for treatments, warn against self-medicating due to potential risks, and recommend seeking a specialized endocrinologist or considering additional treatments like Inositol, Berberine, and dermaneedling.
community Fin is working; I’m just now noticing
The user reports significant hair density improvement after 8.5 months of using finasteride, with no side effects except for initially watery semen. They also mention increased sex drive, which they attribute to finasteride, and regret not starting the treatment earlier due to fear of side effects.
community Dutasteride is way more effective than Finasteride (Study)
Dutasteride is more effective than Finasteride for hair loss, with similar safety profiles. Individual responses vary, and factors like Minoxidil use and age differences may influence results.
community Story time! The Great Unbalding (PP405)
PP405 is a promising new hair loss treatment that may reactivate dormant hair follicles without side effects. It could surpass traditional treatments like minoxidil and finasteride if successful in further trials.