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Research

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research associations between serum dihydrotestosterone levels, lipid parameters & anthropometric measurements in male patients with type 2 diabetes mellitus

July 2022 in “International Journal of Health Sciences (IJHS) (En línea)”

In this study, researchers found that serum dihydrotestosterone levels were significantly lower in individuals with Type 2 Diabetes compared to healthy controls, with 90% of diabetics displaying subnormal levels.

research The Effect of 5α-Reductase Inhibition with Dutasteride and Finasteride on Semen Parameters and Serum Hormones in Healthy Men

195 citations , February 2007 in “The Journal of Clinical Endocrinology and Metabolism”

In this study, administering 5alpha-reductase inhibitors reduced dihydrotestosterone levels and was associated with mild, reversible decreases in semen parameters in healthy men.

research The Effect of 5α-Reductase Inhibition with Dutasteride and Finasteride on Semen Parameters and Serum Hormones in Healthy Men

January 2008 in “Yearbook of Endocrinology”

Dutasteride and finasteride can change semen and hormone levels in men.

research Association between the serum estrone-to-estradiol ratio and parameters related to glucose metabolism and insulin resistance in women with polycystic ovary syndrome

4 citations , December 2021 in “Clinical and Experimental Reproductive Medicine”

This study found that women with PCOS who had a higher serum estrone-to-estradiol ratio were more likely to exhibit higher fasting insulin and postprandial glucose levels, even after adjusting for BMI and waist-to-hip ratio.

research A 2% Oleosome-FGF-2 Fusion Extract Scalp Serum Improves Photo-trichogramDerived Hair Density, Anagen/Telogen Ratio, Hair Shaft Thickness, and Scalp Barrier Parameters in Women with Shedding-Prone Hair: A Randomized, SingleBlind, Placebo-Controlled Pilot Study

July 2026 in “International Journal of Clinical & Experimental Dermatology”

This exploratory pilot study reported that using a 2% Oleosome-FGF-2 fusion extract scalp serum twice daily for 84 days in women with telogen effluvium and brittle hair improved hair density, anagen/telogen ratio, hair shaft thickness, and scalp hydration compared to a placebo.

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Community Join

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community Unexpected Serum DHT Elevation after Generic Dutasteride Use.

in Finasteride/Dutasteride 38 upvotes 1 year ago

Switching from finasteride to a generic dutasteride led to unexpectedly high DHT levels, prompting a switch to a reputed brand and consideration of softgel capsules for better absorption. The user plans to retest DHT levels and may return to finasteride if issues persist.

community Research Backed Dutasteride Simulator (Serum/scalp DHT included for all doses)

in Research 598 upvotes 1 year ago

A Dutasteride Simulator predicts serum dutasteride, serum DHT, and scalp DHT levels using models from research papers. It simulates various dosing schedules to determine steady-state effects and visualizes outcomes, including hair growth-related scalp DHT suppression.

community 📈 Solving for very low dose topical finasteride titration intervals

in Research/Science 30 upvotes 2 years ago

The conversation discusses using very low dose topical finasteride to achieve specific serum DHT reduction percentages. It concludes that finasteride dosage increases linearly between 5-30% DHT reduction but requires exponential increases for reductions up to 70%.

community Is finasteride just not working for me? test results

3 upvotes 1 year ago

A 21-year-old is experiencing aggressive hair loss and questions the effectiveness of finasteride after 45 days of use, with high DHT levels. A user advises that scalp DHT, not serum DHT, is important for hair loss assessment, and suggests monitoring hair improvement over time.

community Doctor said exosome therapy is so painful that one of his patients tried to choke him mid-session

30 upvotes 3 months ago

The user visited a dermatologist for hair loss and was prescribed finasteride and minoxidil tablets, along with a caffeine hair serum. They decided against painful and costly treatments like PRP and exosome therapy, opting instead to stick with medications and possibly accept going bald.

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Learn

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learn Hyaluronic Acid

What’s the difference between using hyaluronic acid as a serum on the scalp versus taking it as a supplement? A serum sits on the scalp surface. Oral hyaluronic acid has small trials on facial wrinkles, none on the scalp or hair.

learn Baicapil

Could a daily serum with Baicapil help revive dormant hair follicles before it’s too late? There is no independent evidence that Baicapil revives dormant follicles; the only human data are the supplier's own unpublished test. A dermatologist can tell whether follicles are still active and which treatments have evidence.

learn Bimatoprost

Can a lash-growth serum like bimatoprost actually work for your scalp? Bimatoprost (Latisse) is FDA-approved only for eyelashes, not the scalp. In the larger of two Allergan phase 2 scalp trials, every bimatoprost formulation gave smaller hair-count gains than minoxidil 5%; the results were posted to ClinicalTrials.gov but never published in a journal, and scalp use remains off-label and experimental.

learn Exosomes

Are exosomes applied as a serum, an injection, or combined with other hair treatments? Clinics offer exosomes as scalp injections, as serums applied after microneedling, or combined with PRP. No exosome product is FDA-approved, and no reliable evidence shows that any of these methods works.

learn Omega 3

Can topical omega-3 oils or serums nourish the scalp, and is taking omega-3 by mouth any better? There is little evidence that omega-3 helps hair, whether taken by mouth or applied to the scalp.

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Clinics

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Hair Loss Treatments
Clínica SerumMérida, Yucatán · MX

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