July 2024 in “The Egyptian Journal of Hospital Medicine” In this study, researchers observed that serum calprotectin levels were higher in alopecia areata patients compared to controls, yet this difference was not statistically significant, and calprotectin was not a reliable predictor of disease activity in alopecia areata patients.
April 2025 in “Egyptian journal of Immunology” In this study, researchers reported significantly higher serum calprotectin levels in alopecia areata patients compared to controls and that these levels were associated with the disease's severity, type, duration, and nail involvement, suggesting calprotectin as a potential marker for inflammation in these patients.
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September 2021 in “Microbiology Spectrum” This study found that multimetal starvation by the immune protein calprotectin triggers unique regulatory responses in Pseudomonas aeruginosa, beyond those seen with individual metal shortages.
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May 2020 in “Anais Brasileiros de Dermatologia” This study found that serum ischemia-modified albumin levels were significantly higher in patients with telogen effluvium compared to healthy controls, suggesting a potential role of oxidative stress in the condition's pathogenesis.
October 2023 in “Research Square (Research Square)” In this study, researchers found that patients with new-onset mild alopecia areata had higher levels of oxidative stress markers and reduced antioxidant levels compared to healthy individuals, suggesting that oxidative stress might play a role in the condition.