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research Elucidating the roles of three β-glucuronosyltransferases (GLCATs) acting on arabinogalactan-proteins using a CRISPR-Cas9 multiplexing approach in Arabidopsis

28 citations , May 2020 in “BMC plant biology”

This study concluded that GLCAT14A-C genes are crucial for the function of glucuronic acid transfer to AGPs in Arabidopsis, affecting various growth and reproductive traits such as seed germination and root hair growth.

research Para rubber seed oil: The safe and efficient bio‐material for hair loss treatment

6 citations , November 2020 in “Journal of cosmetic dermatology”

This study found that standardized para rubber seed oil may be a safe and effective bio-oil for stimulating hair growth and reducing hair loss, exhibiting comparable effects to minoxidil, dutasteride, and vitamin C in certain laboratory settings.

research Enhancing germination performance and vigor of lettuce and napa cabbage seeds through simple seed priming techniques under controlled conditions

1 citations , July 2026 in “Asian Journal of Agriculture”

In this study conducted under controlled laboratory conditions, warm water and shallot extract were found to significantly speed up the germination of lettuce and napa cabbage seeds compared to untreated seeds, though further testing is needed in nursery or field settings.

research Activation of Hair Cell Growth Factors by Linoleic Acid in Malva verticillata Seed

17 citations , April 2021 in “Molecules/Molecules online/Molecules annual”

This study found that linoleic acid from Malva verticillata seed extracts may promote hair follicle cell growth and counteract hair loss signaling in a lab setting.

research Hemp Seed-Derived Exosomes Protect Against Dihydrotestosterone-Induced Hair Growth Inhibition

April 2025 in “Research Square (Research Square)”

In this chicken embryo study, E40 hemp seed callus-derived exosomes counteracted DHT-induced inhibition of hair follicle development, suggesting potential for alopecia treatment and hair follicle regeneration.

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Community Join

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community Shedding and sides from pumpkin seed oil? This sounds ridiculous...

2 upvotes 9 years ago

Pumpkin seed oil may cause side effects similar to finasteride, such as brain fog, lethargy, and reduced libido, but it hasn't shown positive results for hair loss. Users suggest reducing the dosage or consulting a doctor, and other treatments like finasteride, minoxidil, and hair transplants are mentioned as alternatives.

community A person advised me to use pumpkin seed oil instead of minoxidil?

in Minoxidil 10 months ago

Pumpkin seed oil is not a substitute for minoxidil; it acts more like finasteride as a DHT blocker. Minoxidil is necessary for hair growth, and combining it with treatments like PRP or saw palmetto may be beneficial.

community So I've been using Pumpkin Seed Oil for 6 months now

3 upvotes 8 years ago

The user has been using pumpkin seed oil (PSO) for hair loss for 6 months but is unsure of its effectiveness compared to minoxidil. They are considering switching to finasteride due to its proven results, despite concerns about side effects.

community Please be consistent and don't give up!

in Is this regrowth? 418 upvotes 9 months ago

A 29-year-old man regained his hairline using a consistent routine of topical minoxidil and finasteride, along with pumpkin seed oil, despite experiencing side effects like low libido and ED. He emphasizes the importance of consistency and is satisfied with his progress, choosing to avoid oral treatments due to potential side effects.

community Does alfatradiol do anything to help? Is anyone actually using this?

in Product 4 upvotes 11 months ago

Alfatradiol is used as a mild treatment to slow or stabilize hair loss, often alongside finasteride and pumpkin seed oil. Users report reduced shedding and minimal side effects, but minoxidil is noted as more effective for regrowth.

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Learn

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learn Pumpkin seed oil

Does pumpkin seed oil block DHT, the hormone linked to male and female pattern baldness? Pumpkin seed oil has not been shown to lower DHT in people. One small, supplier-funded trial of a branded supplement reported more hair after 24 weeks but did not measure DHT (Cho et al. 2014).
Is pumpkin seed oil more effective as a capsule supplement or as a topical scalp treatment? No study has compared capsules with scalp use. The one human trial, funded by the capsule supplier, used capsules; scalp use has only been tested in mice.
Can pumpkin seed oil be safely combined with other hair growth ingredients like minoxidil or biotin? No study has tested whether pumpkin seed oil is safe or useful alongside minoxidil or biotin. Ask a pharmacist before combining supplements with a hair-loss medicine, and tell your doctor about biotin before blood tests.
All 5 questions on Pumpkin seed oil →