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GlossaryS100 Proteins (S100 family)

calcium-binding proteins involved in cell regulation and signaling

S100 Proteins are a family of calcium-binding proteins involved in various intracellular and extracellular functions, such as regulation of protein phosphorylation, enzyme activities, and cell growth and differentiation. They are implicated in several diseases, including cancer, neurodegenerative disorders, and inflammatory conditions, making them significant both in basic biological research and clinical diagnostics.

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research Isolation and Characterization of Human Repetin, a Member of the Fused Gene Family of the Epidermal Differentiation Complex

77 citations , April 2005 in “Journal of Investigative Dermatology”

Repetin is a protein involved in skin and hair development, binding calcium and compensating for other proteins when needed.

research Characterization of the Cysteine-Rich Calcium-Binding S100A3 Protein from Human Hair Cuticles

17 citations , December 2002 in “Biochemical and biophysical research communications”

Scientists found out how a specific protein in human hair cuticles behaves and is structured.

research S100A6: Molecular Function and Biomarker Role

50 citations , September 2023 in “Biomarker Research”

S100A6 is important for cell functions and can help diagnose and treat diseases.

research Localization of S100A2, S100A4, S100A6, S100A7, and S100P in the Human Hair Follicle

9 citations , July 2014 in “PubMed”

Different S100 proteins have specific roles in various parts of the hair follicle.

research Trichohyalin-Like Proteins Have Evolutionarily Conserved Roles in the Morphogenesis of Skin Appendages

68 citations , April 2014 in “Journal of Investigative Dermatology”

Trichohyalin-like proteins are essential for the development of skin structures like hair, nails, and feathers.

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community What the hell happened in my family genes?

in Chat 116 upvotes 1 year ago

A user is frustrated about early balding despite older male relatives retaining hair into old age. Another user plans to start finasteride soon to address their hair thinning.

community Anyone else’s loved ones just blatantly gaslight you over your hair ?

in Finasteride/Dutasteride 196 upvotes 2 years ago

User discusses resentment towards people who dismissed their hair loss concerns and continued to do so even after a specialist confirmed it. Others share similar experiences and discuss the impact of hair loss on self-esteem and societal perceptions.

community Why do people feel the need to comment on my hair when they know there's nothing I can do about it?

in Chat 72 upvotes 1 year ago

A 28-year-old started using finasteride and minoxidil for hair loss and is frustrated by insensitive comments from others about his balding, which is a sensitive topic for him. People, including a girl he's seeing, have made hurtful remarks, and the conversation includes discussions on societal double standards and advice to ignore such comments and focus on self-improvement.

community In my opinion baldness is more prevalent now and it's being ignored..

in Chat 236 upvotes 2 years ago

The conversation is about the prevalence of baldness among young men and the potential factors contributing to it. Specific treatments mentioned include minoxidil and finasteride.

community Goodbye y'all, it's been a journey but have accepted where I'm at

in Update 219 upvotes 2 years ago

The conclusion of this conversation about hair loss is that the user, y00sh420, tried various treatments including a $700 lllt helmet, topical minoxidil and finasteride, spectraDNC, and micro needling, but did not achieve the desired results. They have decided to stop trying until a cure for male pattern baldness is found. Other users expressed different opinions on hair loss treatments.

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