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    Did you mean Retinoid X Receptors?
    GlossaryRetinoid X Receptor

    regulates gene expression by binding to specific DNA sequences

    The Retinoid X Receptor (RXR) is a type of nuclear receptor that plays a crucial role in regulating gene expression. It binds to specific DNA sequences and partners with other receptors to control various biological processes, including cell growth, differentiation, and metabolism. RXRs are important in the context of skin health and hair growth, as they can influence the activity of genes involved in these processes.

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      the gold standard retinoid in dermatology that's also helpful for hair regrowth alongside Minoxidil

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      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 3 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community A Nuanced Look at Microdosing Topical Finasteride

      in Finasteride/Dutasteride  85 upvotes 11 months ago
      The conversation discusses using a low dose of topical finasteride to achieve hair benefits with minimal systemic exposure. Users share experiences and opinions on dosing, systemic buildup, and side effects of both topical and oral finasteride.

      community Spironolactone topically with a try ?!

      in Research/Science  1 upvotes 9 months ago
      A 30-year-old male is considering using dutasteride and fluridil for hair loss maintenance and is curious about the effectiveness of topical spironolactone, as he cannot take finasteride. He is also planning a hair transplant.