17 citations
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June 2010 in “Journal of Cosmetic Dermatology” Many women with hard-to-treat acne also have PCOS.
August 2025 in “Scientific Reports” This study found that the protein C4BPA may link insulin resistance and acne vulgaris by influencing lipid metabolism and inflammatory pathways, suggesting it as a potential mediator in the pathogenesis of both conditions.
March 2026 in “IP Indian Journal of Clinical and Experimental Dermatology” This study found that female patients with acne had significantly higher insulin resistance compared to a control group without acne, suggesting that acne could serve as an early clinical marker of insulin resistance in women of reproductive age.
June 2021 in “International Journal of Research in Dermatology” This study found that one-third of females with acne and PCOS also showed insulin resistance, suggesting that women with these conditions should be evaluated for impaired glucose tolerance.
2 citations
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January 2019 in “Egyptian Journal of Dermatology and Venereology” This study found no significant differences in insulin resistance between patients with androgenetic alopecia or acne vulgaris and control groups, but suggests insulin may play a role in the conditions' development.