Search
for

    GlossaryX-linked ichthyosis

    genetic skin disorder causing dry, scaly skin in males

    X-linked ichthyosis, also known as steroid sulfatase deficiency, is a genetic skin disorder that primarily affects males. It is caused by mutations in the STS gene on the X chromosome, leading to a deficiency in the enzyme steroid sulfatase. This results in the accumulation of cholesterol sulfate in the skin, causing dry, scaly skin that often appears at birth or within the first year of life.

    Related Terms

    Sort by

    Research

    30 / 1000+ results