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    Glossary Wnt pathway activator

    stimulates cell growth and development through Wnt signaling

    A Wnt pathway activator is a substance or molecule that stimulates the Wnt signaling pathway, a crucial cell communication system involved in regulating cell growth, development, and differentiation. This pathway plays a significant role in hair follicle development and regeneration, making Wnt activators potential therapeutic agents for conditions like alopecia (hair loss).

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    1. Vitamin B12 Activates the Wnt-Pathway in Human Hair Follicle Cells by Induction of <i>beta</i>-Catenin and Inhibition of Glycogensynthase Kinase-3 Transcription Journal of Cosmetics, Dermatological Sciences and Applications · 2011 · 4 citations
    2. Hordenine Activated Dermal Papilla Cells and Promoted Hair Regrowth by Activating Wnt Signaling Pathway Nutrients · 2023 · 3 citations
    3. Escin Activates Canonical Wnt/β-Catenin Signaling Pathway by Facilitating the Proteasomal Degradation of Glycogen Synthase Kinase-3β in Cultured Human Dermal Papilla Cells Current Issues in Molecular Biology · 2023
    4. Increasing GSH-Px Activity and Activating Wnt Pathway Promote Fine Wool Growth in FGF5-Edited Sheep Cells · 2024
    5. Knockdown of miR-361-5p promotes the induced activation of SHF-stem cells through FOXM1 mediated Wnt/β-catenin pathway in cashmere goats Animal Biotechnology · 2024 · 1 citations
    6. Wnt/β-catenin and ERK pathway activation: The possible mechanism of various light-emitting diode light regulates the proliferation of human outer root sheath cells Journal of The American Academy of Dermatology · 2017
    7. Moracin M promotes hair regeneration through activation of the WNT/β-catenin pathway and angiogenesis Archives of Dermatological Research · 2025
    8. Undariopsis peterseniana Promotes Hair Growth by the Activation of Wnt/β-Catenin and ERK Pathways Marine Drugs · 2017 · 27 citations
    9. Myristoleic Acid Promotes Anagen Signaling by Autophagy through Activating Wnt/β-Catenin and ERK Pathways in Dermal Papilla Cells Biomolecules & therapeutics · 2021 · 8 citations
    10. Activating Wnt/β-catenin signaling pathway for disease therapy: Challenges and opportunities Pharmacology & Therapeutics · 2018 · 140 citations
    11. Wnt/β-catenin signaling pathway activates melanocyte stem cells in vitro and in vivo Journal of Dermatological Science · 2016 · 45 citations
    12. Wnt/β‐catenin and ERK pathway activation: A possible mechanism of photobiomodulation therapy with light‐emitting diodes that regulate the proliferation of human outer root sheath cells Lasers in Surgery and Medicine · 2017 · 43 citations
    13. 5-Bromo-3,4-dihydroxybenzaldehyde Promotes Hair Growth through Activation of Wnt/β-Catenin and Autophagy Pathways and Inhibition of TGF-β Pathways in Dermal Papilla Cells Molecules · 2022 · 7 citations
    14. Food‐related botanical Cacumen Platycladi alleviates androgenetic alopecia through activating the W nt/β‐catenin pathway Journal of the Science of Food and Agriculture · 2026
    15. Hair-growth Promoting Effect of Grateloupia elliptica Via the Activation of Wnt Pathway Korean Journal of Pharmacognosy · 2016
    16. Low‐level laser activates Wnt/β‐catenin signaling pathway‐promoting hair follicle stem cell regeneration and wound healing: Upregulate the expression of key downstream gene Lef 1 Skin Research and Technology · 2024 · 2 citations
    17. Pilose antler extracts promotes hair growth in androgenetic alopecia mice by activating hair follicle stem cells via the AKT and Wnt pathways Frontiers in Pharmacology · 2024
    18. The Molecular Mechanism of Natural Products Activating Wnt/β-Catenin Signaling Pathway for Improving Hair Loss Life · 2022
    19. KY19382 Accelerates Cutaneous Wound Healing via Activation of the Wnt/β-Catenin Signaling Pathway International Journal of Molecular Sciences · 2023 · 18 citations
    20. Piperonylic Acid Promotes Hair Growth by Activation of EGFR and Wnt/β-Catenin Pathway International Journal of Molecular Sciences · 2024 · 5 citations
    21. Pre-aggregation of scalp progenitor dermal and epidermal stem cells activates the WNT pathway and promotes hair follicle formation in in vitro and in vivo systems Stem Cell Research & Therapy · 2019 · 17 citations
    22. 25742 Evaluation of the active ingredient complex of an anti-hair loss shampoo on the activation of Wnt/betacatenin pathway in human hair follicle dermal papilla cells Journal of the American Academy of Dermatology · 2021
    23. Characterization of Growth Secondary Hair in Min Pig Activated by Follicle Stem Cell Stimulated by Wnt and BMP Signaling Pathway Animals · 2023 · 1 citations
    24. Isoalantolactone (ISA) Stimulates Hair Cell Growth Through Activation of the WNT/β-catenin and Ras/MAPK Pathways Korean Journal of Pharmacognosy · 2025
    25. 3-Hydroxypropionic Acid Enhances Hair Growth-Related Signaling in Human Follicle Dermal Papilla Cells via Activation of the Wnt/β-Catenin Pathway International Journal of Molecular Sciences · 2026
    26. Hair growth‐promotion effects of different alternating current parameter settings are mediated by the activation of Wnt/<i>β</i>‐catenin and MAPK pathway Experimental Dermatology · 2015 · 27 citations
    27. Morroniside regulates hair growth and cycle transition via activation of the Wnt/β-catenin signaling pathway Scientific Reports · 2018 · 25 citations
    28. Dendrobium officinale polysaccharide promotes angiogenesis as well as follicle regeneration and hair growth through activation of the WNT signaling pathway Regenerative Therapy · 2024
    29. Recombinant Type XVII Collagen Promotes Hair Growth by Activating the Wnt/β-Catenin and SHH/GLI Signaling Pathways Cosmetics · 2025
    30. Low Molecular Weight Collagen Peptide (LMWCP) Promotes Hair Growth by Activating the Wnt/GSK-3β/β-Catenin Signaling Pathway Journal of microbiology and biotechnology · 2023