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    Glossary WNT gene family

    group of genes producing proteins for cell signaling pathways

    The WNT gene family consists of a group of genes that produce proteins involved in signaling pathways crucial for cell growth, development, and differentiation. These pathways play a significant role in various biological processes, including embryonic development and the regulation of hair growth, making them important in both normal physiology and disease states like cancer and alopecia.

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    1. Genome-Wide Identification and Characterization of the Wnt Gene Family in Donkey (Equus asinus): Phylogenetic Analysis and Expression Profiling Biology · 2026
    2. Bioinformatic analysis of gene expression data reveals Src family protein tyrosine kinases as key players in androgenetic alopecia Frontiers in Medicine · 2023
    3. Molecular Evolution and Protein Structure Variation of Dkk Family Genes · 2023 · 3 citations
    4. Roles of <i>jumonji</i> and <i>jumonji</i> family genes in chromatin regulation and development Developmental Dynamics · 2006 · 178 citations
    5. Possible Cellular Communication with Human Follicle Dermal Papilla Cells via Secretions from Human Hair Follicle Keratinocytes Journal of St. Marianna University · 2022
    6. Molecular mechanisms of ectodermal dysplasia syndromes Työväentutkimus Vuosikirja · 2004 · 3 citations
    7. Identification of potential key genes and pathways associated with the Pashmina fiber initiation using RNA-Seq and integrated bioinformatics analysis Scientific Reports · 2021 · 36 citations
    8. Molecular cloning and characterization analysis of LEF-1 gene from Inner Mongolia Cashmere Goat 2010 3rd International Conference on Biomedical Engineering and Informatics · 2010 · 1 citations
    9. APCDD1 is a novel Wnt inhibitor mutated in hereditary hypotrichosis simplex Nature · 2010 · 199 citations
    10. Transcriptomic Analysis Provides Molecular Insights into Skin Development in Dezhou Donkey Foals Veterinary Sciences · 2026
    11. Transcriptome analysis reveals the genetic basis underlying the development of skin appendages and immunity in hedgehog (<i>Atelerix albiventris</i>) bioRxiv (Cold Spring Harbor Laboratory) · 2020
    12. Recessive Mutation in FAM83G Associated with Palmoplantar Keratoderma and Exuberant Scalp Hair Journal of Investigative Dermatology · 2017 · 10 citations
    13. Interplay between EDA-EDAR and WNT signalling pathways in the development of skin appendages in hypohidrotic ectodermal dysplasia Pediatria i Medycyna Rodzinna · 2025 · 1 citations
    14. Suppression of Wnt/β-catenin signaling by EGF receptor is required for hair follicle development Molecular Biology of the Cell · 2018 · 25 citations
    15. Hairless triggers reactivation of hair growth by promoting Wnt signaling Proceedings of the National Academy of Sciences of the United States of America · 2005 · 137 citations
    16. Hairless controls hair fate decision via Wnt/β–catenin signaling Biochemical and Biophysical Research Communications · 2017 · 6 citations
    17. Crosstalk between androgen and Wnt/β-catenin leads to changes of wool density in FGF5-knockout sheep Cell Death and Disease · 2020 · 23 citations
    18. TGFβ family mimetic peptide promotes proliferation of human hair follicle dermal papilla cells and hair growth in C57BL/6 mice Biomedical dermatology · 2018 · 9 citations
    19. CD133-positive dermal papilla-derived Wnt ligands regulate postnatal hair growth Biochemical Journal · 2016 · 15 citations
    20. Wnt target gene Ascl4 is dispensable for skin appendage development bioRxiv (Cold Spring Harbor Laboratory) · 2024
    21. Hairless and Wnt Signaling: Allies in Epithelial Stem Cell Differentiation Cell Cycle · 2006 · 74 citations
    22. In vivo transcriptional governance of hair follicle stem cells by canonical Wnt regulators Nature Cell Biology · 2014 · 173 citations
    23. Expression of the Wnt signaling pathway and hair follicle development in  Rex rabbits of different ages 2025
    24. Large Scale Gene Expression Profiles of Regenerating Inner Ear Sensory Epithelia PLoS ONE · 2007 · 77 citations
    25. Gene Expression Profiling of the Intact Dermal Sheath Cup of Human Hair Follicles Acta dermato-venereologica · 2018 · 11 citations
    26. Clinical course of the first Japanese family with Marie Unna hereditary hypotrichosis: a follow-up report European Journal of Dermatology · 2018
    27. An Intrinsic Oscillation of Gene Networks Inside Hair Follicle Stem Cells: An Additional Layer That Can Modulate Hair Stem Cell Activities Frontiers in Cell and Developmental Biology · 2020 · 23 citations
    28. Marie Unna hereditary hypotrichosis: A Turkish family with loss of eyebrows and a <i>U2HR</i> mutation American Journal of Medical Genetics - Part A · 2010 · 11 citations
    29. Transcriptome Dynamics Reveal Stage-Specific and Melatonin-Triggered Gene Expression Patterns During The Cashmere Growth Cycle in Capra Hircus Research Square (Research Square) · 2021
    30. Hairy Math: Addition of Wnt-3a to Multiply Bulge Cells Journal of Investigative Dermatology · 2015