17 citations
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May 2019 in “Diabetes and Metabolic Syndrome: Clinical Research and Reviews” This study found that fasting insulin levels are associated with increased cardiovascular and metabolic risk factors in women with polycystic ovary syndrome.
This study found that women with PCOS had significant hormonal imbalances, increased central obesity, and a lower 2D:4D digit ratio, suggesting prenatal androgen exposure may play a role in the condition's development.
9 citations
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March 2022 in “Frontiers in Endocrinology” This study found that PCOS is common among Iranian women, with phenotypes involving hyperandrogenism exhibiting worse lipid profiles and higher rates of metabolic syndrome compared to healthy women.
18 citations
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January 2015 in “Journal of obesity and weight loss therapy” This study found that an 8-week low-starch/low-dairy diet led to weight loss, improved insulin sensitivity, and reduced testosterone levels in women with PCOS.
2 citations
,
June 2024 in “Journal of the Pakistan Medical Association” In this cross-sectional study, researchers found that those without a diabetic background had higher levels of secreted frizzled related protein-4, while family history of diabetes was strongly correlated with waist circumference, waist-to-height ratio, and insulin resistance but not significantly linked to protein-4 levels.
30 citations
,
November 2018 in “Fertility and Sterility” This study found that young women with polycystic ovary syndrome had a higher risk of developing hypertension and metabolic syndrome compared to healthy controls, although these risks decreased after age 40.
8 citations
,
May 2021 in “Reproductive Biology and Endocrinology” This study found that using age-specific AMH cut-off levels can help better identify PCOS patients across different age groups from 20 to 40 years.
7 citations
,
October 2020 in “INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH” This study found that stress plays a significant role in altering phenotypic features and body composition among PCOS patients, potentially worsening due to the COVID-19 pandemic.
December 2025 in “Reports of Morphology” This study found that young adult Ukrainian men with alopecia areata had significantly different skinfold thickness at several body sites compared to healthy peers, suggesting unique patterns of fat distribution associated with the disease.
October 2025 in “Journal of Bahria University Medical and Dental College” In this study, among women with polycystic ovary syndrome, free testosterone was most frequently elevated, highlighting its importance in biochemical assessment and suggesting the need for age-related interpretation of DHEAS levels.
4 citations
,
April 2014 in “Lasers in Surgery and Medicine” This observational study reports that a TRASER device using specific wavelengths for vascular and follicular targets showed both clinical responses and histological changes, suggesting its potential as an effective vascular and hair removal tool.
7 citations
,
January 2016 in “Laboratory Investigation” TR3 is mainly found in hair follicle stem cells and may be involved in hair loss.
79 citations
,
December 1999 in “Mechanisms of Development” Whn is crucial for hair growth in certain areas by controlling a specific gene.
5 citations
,
January 2010 in “The anatomical record” This study assessed hair whorl characteristics in domestic dogs and found that simple whorls predominate, with tufted whorls more common in specific regions like elbows and chests, influenced by factors such as coat traits and source.
72 citations
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October 2009 in “The FASEB journal” This study found that thyrotropin-releasing hormone (TRH) acts as a potent stimulator of hair growth in human scalp hair follicles, promoting elongation and prolonging the anagen phase.
46 citations
,
September 2013 in “PLOS ONE” This study identified thyrotropin-releasing hormone (TRH) as a stimulant of wound healing in both frog and human skin models, suggesting it as a potential neuroendocrine wound repair promoter.
59 citations
,
November 2011 in “Development” This study found that the transcription factor Trps1 acts as a novel regulator of the Wnt signaling pathway and early hair follicle progenitors in developing vibrissa follicles in mice.
14 citations
,
May 2013 in “Experimental Dermatology” This study found that the modified wash test was generally more effective than TrichoScan® for diagnosing hair loss, particularly telogen effluvium, though both methods showed only fair concordance with clinical diagnosis.
August 2003 in “Dermatologic Surgery” This study identified five distinct natural scalp whorl patterns and noted that White males have more distinct whorls, whereas African Americans and women often display a diffusion pattern.
18 citations
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July 2003 in “Dermatologic Surgery” This study identified five distinct scalp whorl patterns, noting that white males have the most distinct whorls, while African Americans and women more often exhibit a diffusion pattern.
January 2013 in “edoc (University of Basel)” This study found that TRF1 plays a crucial role in maintaining pluripotency and stem cell compartments, but it is not a suitable in vivo telomere length marker.
69 citations
,
August 1999 in “Developmental biology” This study found that ectopic expression of Whn in transgenic mice caused impaired differentiation in epidermis and hair follicles, with hair growth defects and severe urinary tract issues leading to hydronephrosis.
6 citations
,
October 2012 in “Journal of Heredity” This study identified the Itpr3 gene as responsible for the tufted hair loss phenotype in the BTBR mouse strain.
June 2022 in “Journal of Dermatology Research” This study found that 448-kHz Capacitive-Resistive Electrothermal Therapy led to a significant increase in hair density in women with Female Pattern Hair Loss, likely due to stimulated proliferation of dermal papilla cells.
124 citations
,
December 2016 in “Pharmaceuticals” This review discusses the functions and potential therapeutic targeting of TRP ion channels in the skin, noting their involvement in both physiological processes and various pathological conditions, but reports no new experimental results.
October 2024 in “Journal of the Endocrine Society” This case report highlights that a patient with resistance to thyroid hormone was misdiagnosed as having Graves’ disease, leading to unnecessary radioactive iodine treatment.
29 citations
,
March 2008 in “Dermatologic Surgery” This study developed a prototype device that suggests potential for diagnosing changes in hair quantity, diameter, and density, though formal clinical studies are needed to confirm these findings.
111 citations
,
April 2000 in “British journal of dermatology/British journal of dermatology, Supplement” In this study, physiological levels of free T3 significantly enhanced the survival of human hair follicles in vitro.
5 citations
,
August 2019 in “iScience” In this study, Trf1 genetic deletion in mice, including those with cancer-prone mutations, was shown to not affect overall viability and cause only mild effects, while being necessary for tumor formation, suggesting a potential therapeutic window for Trf1 as an anti-cancer target.
15 citations
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February 2019 in “Journal of clinical medicine” In this animal study, atorvastatin co-administered with trastuzumab reversed trastuzumab-induced cognitive impairment (chemo-brain) and improved its anti-cancer efficacy without causing hair loss.