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In a retrospective cohort of patients with steroid 5 α-reductase 2 deficiency, this study identified seven novel genetic variants in the SRD5A2 gene, expanding the variant database and contributing to improved diagnostic and therapeutic approaches for the condition.

This study found that visual hair density is better correlated with hair count and shaft diameter, leading to the development of the Hair Diameter Index used in planning hair restoration procedures.

This study analyzed the care provided to gender-dysphoric Veterans at VANCHCS and concluded that a more consistent, team-based approach could improve their treatment outcomes.

This study observed that the vitamin D receptor is crucial for hair follicle formation and altering tumor development in the Wnt signaling pathway, suggesting therapeutic potential for vitamin D analogues in related tumors.

This review discusses the role of the unliganded vitamin D receptor in hair follicle cycling and tumor formation in mice and reports no new experimental findings.

This study reported that the combination of a 308-nm excimer lamp and 10% liquor carbonis detergens significantly improved scalp psoriasis symptoms compared to the excimer lamp alone, with more patients achieving 75% reduction in their Psoriasis Scalp Severity Index.

This study found that transplantation of autologous stromal vascular fraction cells increased skin thickness and improved regeneration when combined with mechanical stretching, without severe adverse events.

This study found that both desmoglein-specific and non-desmoglein autoantibodies may play active roles in Pemphigus vulgaris pathogenesis, with HLA genetics influencing autoimmune specificity.

This review highlights significant research trends and challenges in utilizing plant-derived extracellular vesicles for drug delivery and biomedical applications, emphasizing the need for standardized protocols and advanced purification technologies.

This article reviews recent trends and developments in dermoscopy, highlighting its expanding use beyond pigmented lesions, and reports no new clinical results.

The new surgical technique for vitiligo is effective, safe, and cost-efficient.

This study found that nanobubble-encapsulated diclofenac with ultrasound-targeted microbubble destruction (DNBs-UTMD) can enhance the anti-tumor efficacy of Doxil® by regulating the tumor immune microenvironment, improving drug uptake, and increasing T cell responses while reducing immune-suppressive cells in the process.

This study found that the vitamin D receptor is crucial for initiating the postnatal hair follicular cycle in mice, preventing alopecia associated with its inactivation.

The document concludes that detailed clinical descriptions of seven family cases help understand dominant dystrophic epidermolysis bullosa's symptoms and inheritance.

This study highlighted the significant role of VSM in cochlear aging, suggesting that changes in its structure and composition may contribute to the development of various pathologies, including congenital hearing disorders, while also identifying the need for further research on VCM-associated molecules.

This study found that alopecia in VDR-null mice persists despite undetectable vitamin D levels, indicating a defect in epithelial-mesenchymal communication due to the absence of ligand-independent receptor function.

This editorial introduces a special issue on "In Vitro Models of Human Disease" in DMM, highlighting how these models enhance understanding of disease mechanisms, accelerate drug development, and support personalized treatment strategies.

This study found that overexpression of the enzyme ornithine decarboxylase in transgenic mice led to UVB-induced skin tumors, but this was prevented by the ODC inhibitor α-difluoromethylornithine.

This study found that among patients with discogenic low back pain, intradiscal injection of platelet-rich plasma over six months resulted in significant symptom improvement, with 79.3% achieving a clinically important reduction in pain and disability scores, and showed promising safety without treatment-related complications.

In this study, D-OCT imaging revealed distinct structural and vascular changes in patients with frontal fibrosing alopecia, highlighting the technique's potential for diagnosing and monitoring the condition's activity.

In this study, the DIET-AI model, developed from a large dataset of over 200,000 images, demonstrated diagnostic performance for 31 skin diseases comparable to dermatologists of varying experience levels in 15 hospitals across China, supporting its potential effectiveness in clinical settings.

This study reports that Elvitegravir, a drug currently approved for other uses, shows potential as a neuro- and mitoprotective agent by attenuating mitochondrial damage caused by NMDA receptors in primary mouse cortical neurons.

In this retrospective study of eight Saudi children with hereditary vitamin D resistant rickets, researchers observed that adjunctive cinacalcet appeared safe and showed initial promise in improving serum PTH levels, though further investigation is needed to confirm its efficacy.

This Viewpoint discusses the utility of dermoscope in routine practice and how familiarity with dynamic vs static trichoscopy may address its limitations, but it reports no new clinical findings.

This report describes how ultraviolet-induced fluorescence dermoscopy helped accurately diagnose scalp disorders, specifically alopecia areata and tinea capitis, in pediatric patients.

Using a call center to collect data in a trial for eye disease in diabetics led to high response rates and very little missing information.

This study found that two unrelated domestic shorthair cats had novel DSG4 gene mutations causing defective hair shafts, representing the first report of pathogenic DSG4 variants in domestic animals.

This report describes a rare case of porokeratotic eccrine ostial and dermal duct nevus in a 64-year-old woman, successfully treated with CO₂ laser, highlighting its potential occurrence in older adults.

This study found that a spontaneous deletion in the Dsg3 gene of mice leads to hypomorphic desmoglein 3 expression, resulting in severe immunodeficiency, cyclic hair loss, and wasting disease, without causing the blistering typical of pemphigus vulgaris.