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    Glossary U2HR

    non-coding DNA region linked to hair growth regulation

    U2HR stands for "Untranslated 2 Hairless Region." It refers to a specific non-coding region of the human genome that is associated with the regulation of hair growth. Mutations or alterations in this region can lead to conditions like alopecia, where individuals experience hair loss. This area is of particular interest in genetic research related to hair disorders.

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    Research 22

    1. Marie Unna hereditary hypotrichosis: Identification of a U2HR mutation in the family from the original 1925 report Journal of the American Academy of Dermatology · 2011 · 14 citations
    2. Loss-of-function mutations of an inhibitory upstream ORF in the human hairless transcript cause Marie Unna hereditary hypotrichosis Nature Genetics · 2009 · 181 citations
    3. Marie Unna hereditary hypotrichosis: A Turkish family with loss of eyebrows and a <i>U2HR</i> mutation American Journal of Medical Genetics - Part A · 2010 · 11 citations
    4. Identification of a novel heterozygous mutation in the first Japanese case of Marie Unna hereditary hypotrichosis The Journal of Dermatology · 2013 · 6 citations
    5. Marie-unna hereditary hypotrichosis International Journal of Trichology · 2014 · 4 citations
    6. Two females with hair loss Journal der Deutschen Dermatologischen Gesellschaft · 2019
    7. Clinical course of the first Japanese family with Marie Unna hereditary hypotrichosis: a follow-up report European Journal of Dermatology · 2018
    8. Odd-Looking Hair and Progressive Alopecia in Mother and Son JAMA Dermatology · 2014
    9. Biology and Genetics of Hair Annual Review of Genomics and Human Genetics · 2010 · 89 citations
    10. Molecular Genetics of Alopecias Current problems in dermatology · 2015 · 9 citations
    11. Disease causing homozygous variants in the human hairless gene International Journal of Dermatology · 2015 · 7 citations
    12. Hair loss and its management in children Expert Review of Dermatology · 2011 · 5 citations
    13. Development of squamous cell carcinoma from erythroplasia of Queyrat following photodynamic therapy European Journal of Dermatology · 2018 · 3 citations
    14. Inherited Disorders of the Hair Elsevier eBooks · 2013 · 2 citations
    15. Alopezien und Hypotrichosen im Kindesalter Der Hautarzt · 2014 · 5 citations
    16. Recalcitrant Female Pattern Hair Loss Like Alopecia Unveils Unexpected Rare Entity Clinical Cosmetic and Investigational Dermatology · 2025
    17. Genetic Hair Disorders: A Review Dermatology and Therapy · 2019 · 26 citations
    18. A Missense Mutation within the Helix Initiation Motif of the Keratin K71 Gene Underlies Autosomal Dominant Woolly Hair/Hypotrichosis Journal of Investigative Dermatology · 2012 · 78 citations
    19. Novel mutations in the keratin-74 (KRT74) gene underlie autosomal dominant woolly hair/hypotrichosis in Pakistani families Human Genetics · 2010 · 40 citations
    20. Pili Torti: A Feature of Numerous Congenital and Acquired Conditions Journal of clinical medicine · 2021 · 9 citations
    21. A TP63 Mutation Causes Prominent Alopecia with Mild Ectodermal Dysplasia 2020 · 2 citations
    22. Current Genetics in Hair Diseases InTech eBooks · 2013 · 1 citations