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    Glossary TRPV2

    protein channel in cells activated by heat and stress

    TRPV2 is a type of protein found in the cell membranes that acts as an ion channel, allowing certain ions like calcium to pass into the cell. It is activated by high temperatures and mechanical stress, playing a role in various physiological processes, including pain perception and the regulation of hair growth.

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    Research 30 of 477

    1. Activation of TRPV3 Regulates Inflammatory Actions of Human Epidermal Keratinocytes Journal of Investigative Dermatology · 2017 · 77 citations
    2. Structural mechanism of TRPV3 channel inhibition by the plant‐derived coumarin osthole EMBO reports · 2021 · 28 citations
    3. Molecular determinants for the chemical activation of the warmth-sensitive TRPV3 channel by the natural monoterpenoid carvacrol Journal of Biological Chemistry · 2022 · 24 citations
    4. Mechanisms of proton inhibition and sensitization of the cation channel TRPV3 The Journal of General Physiology · 2020 · 15 citations
    5. TRPV Channels in Osteoarthritis: A Comprehensive Review Biomolecules · 2024 · 14 citations
    6. Unlocking the therapeutic potential of TRPV3: Insights into thermosensation, channel modulation, and skin homeostasis involving TRPV3 BioEssays · 2024 · 10 citations
    7. Different Ligands of the TRPV3 Cation Channel Cause Distinct Conformational Changes as Revealed by Intrinsic Tryptophan Fluorescence Quenching 2015 · 7 citations
    8. Therapeutic inhibition of keratinocyte TRPV3 sensory channel by local anesthetic dyclonine 2020 · 3 citations
    9. TRPV3 Ion Channel: From Gene to Pharmacology International Journal of Molecular Sciences · 2023 · 2 citations
    10. The Multifaceted Functions of TRPV4 and Calcium Oscillations in Tissue Repair International journal of molecular sciences · 2024 · 1 citations
    11. Localization of mechanosensitive channel TRPV4 in mouse skin Neuroscience Letters · 2003 · 123 citations
    12. TRPV3 as a Therapeutic Target for Itch Journal of Investigative Dermatology · 2012 · 88 citations
    13. TRPV1 Function in Health and Disease Current Pharmaceutical Biotechnology · 2010 · 65 citations
    14. Influence of TRPV3 mutation on hair growth cycle in mice Biochemical and Biophysical Research Communications · 2007 · 59 citations
    15. Olmsted Syndrome Caused by a Homozygous Recessive Mutation in TRPV3 Journal of Investigative Dermatology · 2014 · 56 citations
    16. Hair Cycle Control by Vanilloid Receptor-1 (TRPV1): Evidence from TRPV1 Knockout Mice Journal of Investigative Dermatology · 2006 · 49 citations
    17. Activation of TRPV3 Inhibits Lipogenesis and Stimulates Production of Inflammatory Mediators in Human Sebocytes—A Putative Contributor to Dry Skin Dermatoses Journal of Investigative Dermatology · 2018 · 26 citations
    18. TRPV4 Is Expressed in Human Hair Follicles and Inhibits Hair Growth In Vitro Journal of Investigative Dermatology · 2018 · 25 citations
    19. Hair Loss Caused by Gain-of-Function Mutant TRPV3 Is Associated with Premature Differentiation of Follicular Keratinocytes 2021 · 11 citations
    20. Dermal TRPV1 innervations engage a macrophage- and fibroblast-containing pathway to activate hair growth in mice Developmental Cell · 2024 · 5 citations
    21. A combination of low-dose systemic etretinate and topical calcipotriol/betamethasone dipropionate treatment for hyperkeratosis and itching in Olmsted syndrome associated with a TRPV3 mutation Journal of dermatological science · 2017 · 5 citations
    22. Transient stimulation of TRPV4‐expressing keratinocytes promotes hair follicle regeneration in mice British Journal of Pharmacology · 2020 · 4 citations
    23. Cutaneous TRPV4 Potentiates the Afferent Transmission of Electroacupuncture Stimulation ACS Omega · 2026
    24. Natural phenylethanoid glycoside forsythoside A alleviates androgenetic alopecia by selectively inhibiting TRPV3 channels in mice European Journal of Pharmacology · 2025
    25. Pathogenesis and management of TRPV3-related Olmsted syndrome Frontiers in Genetics · 2024
    26. Case report: Novel p.Val306Met missense mutation in TRPV3 in a case of Olmsted syndrome accompanied by squamous cell carcinoma Frontiers in Oncology · 2024
    27. Whole genome sequencing analysis of alpaca suggests TRPV3 as a candidate gene for the suri phenotype BMC genomics · 2024
    28. Molecular studies of transient receptor potential Vanilloid 3 (TRPV3) OPAL (Open@LaTrobe) (La Trobe University) · 2024
    29. 738 Cryo-EM and molecular dynamics of TRPV3 channel in activated state reveal structural features implicated in severe itch and hyperkeratosis 2023
    30. Activation of temperature-sensitive Ca2+-permeable TRPV3 channels by natural ï¡-hydroxyl acids causes exfoliation for skin-resurfacing 2020