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Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Planarian regeneration begins with a specific gene activation caused by injury, essential for healing and tissue regrowth.

PGD2 stops hair growth and is higher in bald men with AGA.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

Sebocytes play a key role in controlling androgen levels in human skin.

The ZIP7 gene helps control zinc levels in cells by moving zinc from the Golgi apparatus to the cytoplasm.

Spironolactone is a safe and effective treatment for reducing excessive hair growth in women.

Androgens can help prevent memory problems caused by apoE4.

Certain mutations in a hair growth-related gene cause a type of genetic hair loss.

Jumonji genes are important for development and their mutations can cause abnormalities, especially in the heart and brain.

Some medicinal plants can help heal wounds and may lead to new treatments.

Myrtle has various health benefits and potential for medicine development.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

Current treatments for alopecia show no significant long-term benefits.

Certain inhibitors slow down plant growth by causing early cell specialization without changing the cell development pattern.

DrugNet effectively identifies new uses for existing drugs and may save resources in drug development.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Aging causes skin stem cells to work less effectively.

Transplant success has improved with better immunosuppressive drugs and donor matching.

Trichoscopy can diagnose female hair loss with high accuracy by looking for specific patterns in hair and scalp appearance.

Hair analysis can detect cocaine use but doesn't accurately show the amount or timing of use.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

The human type II 5α-reductase gene, linked to certain male health conditions, has a specific structure and low similarity to other related genes.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

MicroRNA-302 helps improve the conversion of body cells into stem cells by blocking NR2F2.

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.