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Gender-affirming therapy can cause skin issues like acne and hair loss in transgender adolescents, and more research is needed on its dermatological effects.

Testosterone pellets might work for transgender men's hormone therapy, but more research is needed.

Diagnosing osteoporosis in transgender people is challenging due to unclear guidelines and hormone treatment effects.

Transgender and nonbinary individuals experience hair loss, with transmen on testosterone seeing more severe hair loss, while feminizing hormones may stabilize hair loss in transwomen.

Transgender patients in critical care need better-trained medical staff and specific guidelines.

Uterine transplants for transgender women are feasible but need more research.

The document concludes that health care providers should offer culturally competent care and more research is needed to improve health outcomes for transgender individuals.

Genetic counselors should be culturally skilled and aware of transgender patients' unique health risks and needs.

Inclusive and affirming healthcare is essential for improving transgender individuals' quality of life and health.

The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

Gender affects hair and scalp characteristics, with differences in hormone responses, graying patterns, and trace metals.

Minoxidil, finasteride, and low-level laser light therapy are effective FDA-approved treatments for hair loss.

PrEP for HIV is less effective in transgender women mainly due to low adherence to the treatment.

Non-binary transgender individuals need personalized hormonal treatments for better well-being and quality of life.

5α-reductase inhibitors like finasteride may not be effective or safe for transgender individuals, and more research is needed.

AGA treatments like minoxidil and LLLLT are safe and effective for gender minority patients.

Testosterone replacement is recommended for men with low testosterone levels and symptoms of hypogonadism.

A reliable method was developed to measure dutasteride in tablets accurately and consistently.

Hair loss greatly affects quality of life, and dermatologists are crucial for proper diagnosis and treatment.

Female authorship in dermatology publications increased during the COVID-19 pandemic, but women are still underrepresented in senior roles.

Spironolactone is safe for treating female hair loss, but the safety of other drugs is uncertain.

Masculinizing hormone therapy increases the risk of hair loss in transgender and gender-diverse patients.

Transgender and gender-diverse adults on hormone therapy often face drug-hormone interactions, especially with multiple psychotropic medications.

Hormone therapy in transgender and gender diverse individuals affects hair loss differently than in cisgender individuals.

Most transgender patients getting laser hair removal before gender-affirming surgery are already on hormone therapy, which might affect the hair removal process.

Topical minoxidil helps transgender individuals assigned female at birth grow more facial hair.

Feminizing hormone therapy increases kidney filtration rate.

Transgender women can develop feminine traits and improve their quality of life through hormone therapy and surgery, but results vary and access to surgery can be limited.

Hormone therapy in transgender individuals can increase acne and affect hair growth and loss.

Gynecologists should provide comprehensive care for transgender patients, including mental health evaluation, hormone therapy, and surgical options, while monitoring for side effects and ensuring patient safety.