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    Glossary Topical Tofacitinib

    medication applied to skin to treat hair loss

    Topical Tofacitinib is a medication applied directly to the skin to treat conditions like alopecia areata, an autoimmune disorder that causes hair loss. It works by inhibiting Janus kinase (JAK) enzymes, which play a role in the immune response, thereby reducing inflammation and potentially promoting hair regrowth.

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    1. Topical 2% tofacitinib for children with alopecia areata, alopecia totalis, and alopecia universalis Journal of the American Academy of Dermatology · 2018 · 49 citations
    2. Topical tofacitinib solution for the treatment of alopecia areata affecting eyelashes JAAD Case Reports · 2018 · 24 citations
    3. Topical tofacitinib for the treatment of alopecia areata affecting facial hair British Journal of Dermatology · 2021 · 7 citations
    4. Successful Treatment of Severe Alopecia Areata With Oral or Topical Tofacitinib. PubMed · 2018 · 4 citations
    5. Topical tofacitinib for patients with lichen planopilaris and/or frontal fibrosing alopecia Journal of the American Academy of Dermatology · 2024 · 3 citations
    6. Topical tofacitinib in treatment of alopecia areata Einstein (São Paulo) · 2020 · 2 citations
    7. Role of topical tofacitinib in autoimmune skin disorders: An expert opinion IP Indian Journal of Clinical and Experimental Dermatology · 2024 · 1 citations
    8. Use of Excimer Lamp and Topical Tofacitinib 2% Gel in the Treatment of Pediatric Alopecia Areata: A Case Report Cureus · 2025
    9. Exploring the Use of Topical Tofacitinib in Pediatric Alopecia Totalis International Journal of Trichology · 2025
    10. Efficacy and Safety of Topical Tofacitinib for the Treatment of Alopecia Areata Indian Dermatology Online Journal · 2024
    11. 43647 Treatment of Refractory Folliculitis Decalvans with the Topical JAK Inhibitor Tofacitinib Journal of the American Academy of Dermatology · 2023
    12. Treatment of longstanding alopecia areata universalis of the eyebrows/facial hair with oral and topical tofacitinib Dermatology Online Journal · 2022
    13. Topical Delivery of Tofacitinib in Dermatology: The Promise of a Novel Therapeutic Class Using Biodegradable Dendritic Polyglycerol Sulfates Pharmaceuticals · 2024 · 1 citations
    14. FORMULATION AND EVALUATION OF A TOPICAL GEL CONTAINING MINOXIDIL AND TOFACITINIB CITRATE FOR ALOPECIA AREATA International Journal of Applied Pharmaceutics · 2023
    15. Efficacy of topical tofacitinib in promoting hair growth in non-scarring alopecia: possible mechanism via VEGF induction Archives of Dermatological Research · 2017 · 27 citations
    16. 1311 Efficacy of topical tofacitinib in promoting hair growth in non-scarring alopecia Journal of Investigative Dermatology · 2018
    17. A Novel Topical Compound Gel Loading Minoxidil and Tofacitinib for Treatment of Alopecia Areata: Formulation, Characterization, and In Vitro/In Vivo Evaluation Drug Development Research · 2025
    18. Tofacitinib 2% ointment, a topical Janus kinase inhibitor, for the treatment of alopecia areata: A pilot study of 10 patients Journal of the American Academy of Dermatology · 2017 · 48 citations
    19. Simultaneous Estimation of Minoxidil and Tofacitinib Citrate in Bulk and Topical Gel - A Validated UV-spectrophotometric Technique Advances in Pharmacology and Pharmacy · 2024
    20. A pilot study of 2% tofacitinib cream with narrowband ultraviolet B for the treatment of facial vitiligo Journal of The American Academy of Dermatology · 2019 · 25 citations
    21. Nanostructured lipid carriers promote percutaneous absorption and hair follicle targeting of tofacitinib for treating alopecia areata Journal of Controlled Release · 2024
    22. Tofacitinib in the Management of Alopecia Universalis International Journal of Trichology · 2023
    23. Topical Janus kinase inhibitors for the treatment of pediatric alopecia areata Journal of the American Academy of Dermatology · 2017 · 83 citations
    24. Topical JAK Inhibitors for the Treatment of Alopecia Areata and Vitiligo Current dermatology reports · 2017
    25. An excellent response to tofacitinib in a Brazilian adolescent patient with alopecia areata: A case report and a review of the literature Clinical Case Reports · 2019 · 11 citations
    26. Treatment of alopecia universalis with topical Janus kinase inhibitors – a double blind, placebo, and active controlled pilot study International Journal of Dermatology · 2018 · 49 citations
    27. Experience with oral tofacitinib in 8 adolescent patients with alopecia universalis Journal of the American Academy of Dermatology · 2017 · 49 citations
    28. Tofacitinib for the Treatment of Three Immune-mediated Conditions in One Patient: Ulcerative Colitis, Pyoderma Gangrenosum, and Alopecia Areata Inflammatory Bowel Diseases · 2021 · 5 citations
    29. An Excellent Response to Tofacitinib in a Pediatric Alopecia Patient: A Case Report and Review. PubMed · 2018 · 5 citations
    30. SDRIFE Induced by Tofacitinib Indian Journal of Dermatology · 2024 · 3 citations