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Excessive selenium from a supplement caused toxicity but patients recovered with care.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

New treatments for male hypogonadism are effective and should be personalized.

Taking low-dose spironolactone and metformin together works better for PCOS symptoms than either drug alone.

Finasteride is a safe, effective treatment for hirsutism with fewer side effects.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

Finasteride effectively reduces hair growth in women with idiopathic hirsutism, but requires careful contraception during treatment.

PCOS is a common hormonal disorder in women, treated with lifestyle changes and medications like hormonal contraceptives and metformin.

Some treatments, like corticosteroids and sensitizing agents, can help with alopecia areata, but more high-quality research is needed.

Testosterone treatment effectively causes male physical development in transgender male adolescents but may lead to side effects like acne, higher BMI and blood pressure, lower good cholesterol, and decreased bone density.

Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.

Human hair follicles produce and respond to erythropoietin, helping protect against stress.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Many young women who donate blood have hormonal disorders like excess male hormones and PCOS.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.

Stress can worsen skin conditions by affecting hormone levels and immune response.

The document concludes that alopecia areata is an autoimmune disease without a definitive cure, but treatments like corticosteroids are commonly used.

Hirsutism is excessive hair growth in women often caused by polycystic ovarian syndrome, and identifying the cause is important for managing associated health risks.

Androgens cause skin issues like acne and hair growth in women, often due to PCOS, and can be treated with medication and lifestyle changes.

European guidelines recommend regular eye and ear exams, skin care, vitamin D supplements, and cautious use of medications for managing congenital ichthyoses.

Doctors need to be better prepared to assess and treat obesity in patients.

Women with acromegaly often have irregular periods due to hormone imbalances and growth hormone effects.

The document concludes that early recognition and treatment of primary cicatricial alopecia is crucial to prevent permanent hair loss.

Prolactin affects the production of different keratins in human hair, which could lead to new treatments for skin and hair disorders.

A new type of rapid hair loss called ADTA usually gets better on its own within 6 months.

Antidepressants may improve or resolve scalp dysesthesia in most patients.

Finasteride effectively treats male pattern baldness, improving hair growth and density.

Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.

Dermatologists play a key role in treating skin symptoms of PCOS like dark patches, excess hair, acne, and hair loss.