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Cyproterone acetate may cause liver cancer at high doses, but is considered safe at recommended doses for approved uses.

Researchers developed a model to predict how well certain compounds can block an enzyme related to hair loss and prostate issues, suggesting a 50 mg dose of finasteride might be effective based on lab and body data.

A 17-year-old female with adrenogenital syndrome produces very high levels of androgens, which prevent complete feminization despite high estrogen doses.

Clascoterone is safe for the heart, even at high doses.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

New drugs for heart disease may be developed from molecules secreted by stem cells.

The cause of atypical Cushing's syndrome in dogs, possibly linked to sex hormones, is not yet proven.

Children taking higher doses of valproic acid had lower biotinidase activity, which may lead to biotin deficiency, but biotin supplements could help.

Terbinafine quickly builds up in skin and hair, staying effective for over 3 weeks.

Anticancer drugs like methotrexate and trimetrexate could be effective and safe for treating malaria at low doses.

Oral retinoids are effective for severe skin conditions but require careful use due to side effects.

Systemic retinoids are effective for psoriasis but have side effects; benefits may outweigh risks, especially when reducing cancer risks from other treatments.

Finasteride doesn't affect antipyrine metabolism, so interactions with cytochrome P-450 enzyme drugs are unlikely.

Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.

Oral retinoids are effective for various skin conditions but have side effects and should not be used during pregnancy.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

Stem cells help repair tissue mainly by releasing beneficial substances, not by replacing damaged cells.

Levetiracetam is widely used and generally well-tolerated for treating idiopathic generalized epilepsies, with tiredness as the main side effect.

Oral retinoids are effective for treating severe skin disorders but have reversible side effects and risks for pregnant women.

Acitretin is effective for severe psoriasis and can be used long-term due to no immunosuppression, but must be carefully monitored for side effects and is not for pregnant women.

Itraconazole-loaded nanoparticles are more effective and less toxic for treating fungal infections than conventional oral itraconazole.

Blocking DGAT1 reduces oil gland size in mice and dogs, but only mice experience hair loss.

Terazosin and finasteride together cause no major issues.

Flutamide caused damage to male rat reproductive organs and may affect fertility.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Hormonal treatments can help with acne, especially in women, by lowering androgen levels or blocking their effects.

Finasteride effectively reduces hair loss by decreasing androgen levels.

Using minoxidil on dogs can cause serious cardiovascular damage, including arterial injury and hemorrhagic lesions.

Wnt10b helps blood stem cells grow after injury.

The LRRK2-G2019S mutation in Parkinson's disease has a lifetime penetrance of 25-35%, and finasteride may help reduce symptoms in adult male Tourette syndrome patients.