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    Glossary Telomerase Reverse Transcriptase

    enzyme that maintains telomere length, crucial for cell division

    Telomerase Reverse Transcriptase (TERT) is an enzyme that helps maintain the length of telomeres, which are protective caps at the ends of chromosomes. By adding repetitive nucleotide sequences to the telomeres, TERT plays a crucial role in cellular aging and replication. This enzyme is particularly active in stem cells, germ cells, and cancer cells, allowing them to divide indefinitely.

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    Research 30 of 570

    1. The Telomerase Reverse Transcriptase (TERT) Gene Molecular Characterization in Sheep and the Association of Its Variation with Wool Traits Animals · 2026
    2. Perspectives in dermatopathology: telomeres and telomerase in ageing and cancer; with emphasis on cutaneous disease Journal of Cutaneous Pathology · 2000 · 11 citations
    3. Molecular Regulation of Melanocyte Senescence Pigment Cell Research · 2002 · 85 citations
    4. Dermal papilla cells induce keratinocyte tubulogenesis in culture Histochemistry and cell biology · 2010 · 28 citations
    5. Fisetin Promotes Hair Growth by Augmenting TERT Expression Frontiers in Cell and Developmental Biology · 2020 · 22 citations
    6. TERT/BMI1-transgenic human dermal papilla cells enhance murine hair follicle formation in vivo Journal of Dermatological Science · 2022 · 1 citations
    7. Study of Drug Target Identification and Associated Molecular Mechanisms for the Therapeutic Activity and Hair Follicle Induction of Two Ashwagandha Extracts Having Differential Withanolide Constitutions Journal of Nutrition and Metabolism · 2023
    8. Establishment and characterization of an immortalized human dermal papilla cell line BMB Reports · 2011 · 21 citations
    9. Novel in vitro culture condition improves the stemness of human dermal stem/progenitor cells Molecules and Cells · 2013 · 18 citations
    10. Establishment and characterization of five immortalized human scalp dermal papilla cell lines Biochemical and Biophysical Research Communications · 2018 · 16 citations
    11. Dermal papilla cells induce keratinocyte tubulogenesis in culture Elina S. ChermnykhEkaterina A. VorotelyakKsenia Y. Gnedeva • Marianna V. MoldaverYegor E. YegorovAndrey V. Vasiliev • 2010
    12. The use of polyethylenimine–DNA to topically deliver hTERT to promote hair growth Gene Therapy · 2011 · 17 citations
    13. New intranasal and injectable gene therapy for healthy life extension bioRxiv (Cold Spring Harbor Laboratory) · 2021
    14. Establishment and characterization of matched immortalized human frontal and occipital scalp dermal papilla cell lines from androgenetic alopecia Scientific Reports · 2023
    15. Combinatorial expression of cell cycle regulators is more suitable for immortalization than oncogenic methods in dermal papilla cells iScience · 2021 · 5 citations
    16. Causality of Aging Hallmarks Aging and Disease · 2025 · 1 citations
    17. Identifying molecular targets for reverse aging using integrated network analysis of transcriptomic and epigenomic changes during aging Scientific Reports · 2021 · 12 citations
    18. Wasabi leaf extract changes the expression levels of cytokine related genes in dermal papilla cells, which identified by the whole transcriptome 2025
    19. Stem cells and aberrant signaling of molecular systems in skin aging Ageing Research Reviews · 2014 · 25 citations
    20. Effects of a complex mixture prepared from agrimonia, houttuynia, licorice, peony, and phellodendron on human skin cells Scientific Reports · 2020 · 4 citations
    21. Normal and Aging Hair Biology and Structure ‘Aging and Hair' Current problems in dermatology · 2015 · 20 citations
    22. Opposing impacts on healthspan and longevity by limiting dietary selenium in telomere dysfunctional mice Aging Cell · 2016 · 30 citations
    23. Loss of Ten1 in mice induces telomere shortening and models human dyskeratosis congenita Science Advances · 2025 · 3 citations
    24. Telomere dysfunction impairs epidermal stem cell specification and differentiation by disrupting BMP/pSmad/P63 signaling PLOS genetics · 2019 · 19 citations
    25. Telomere Dynamics and Telomerase in the Biology of Hair Follicles and their Stem Cells as a Model for Aging Research Journal of Investigative Dermatology · 2021 · 12 citations
    26. Conditional telomerase induction causes proliferation of hair follicle stem cells Nature · 2005 · 414 citations
    27. Transcriptome analysis to identify the downstream genes of androgen receptor in dermal papilla cells BMC Genomic Data · 2022 · 1 citations
    28. The Use of Stem Cell Differentiation Stage Factors (SCDSFs) Taken from Zebrafish Embryos during Organogenesis and Their Role in Regulating the Gene Expression of Normal and Pathological (Stem) Cells International Journal of Molecular Sciences · 2020 · 3 citations
    29. The role of SFRP1 in human dermal papilla cell growth and its potential molecular mechanisms as a target in regenerative therapy Regenerative Therapy · 2024
    30. Editorial: Directing Stem Cell Fate Using Plant Extracts and Their Bioactive Compounds Frontiers in Cell and Developmental Biology · 2022 · 4 citations