129 citations,
January 2004 in “Journal of medicinal chemistry” Researchers developed new compounds that target the androgen receptor effectively with fewer side effects.
19 citations,
January 1997 in “Dermatologic Clinics” Most treatments for hair loss in 1997 were not effective for most people, and maintaining hair growth was difficult.
1 citations,
April 2009 in “Cochrane Database of Systematic Reviews” Review finds no permanent solution for female hair loss.
[object Object] 11 citations,
August 1997 in “Expert Opinion on Therapeutic Patents” Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.
22 citations,
May 2011 in “European Journal of Cancer” The drug combination was safe and showed promise in treating advanced tumors.
1 citations,
November 2021 in “Biomedicines” Understanding how acne develops in different diseases could lead to new treatments.
1 citations,
February 2004 Skin diseases are common and can significantly affect people's lives; better outcome measures and ethical clinical trials are needed to improve dermatology care.
1 citations,
January 2009 in “Cochrane Database of Systematic Reviews” Review determines effective, safe treatments for female hair loss.
87 citations,
July 2012 in “Expert Review of Clinical Immunology” Pregnancy can increase lupus activity, but careful planning and treatment can improve outcomes.
January 2018 in “Springer eBooks” Cancer treatments targeting specific cells often cause skin, hair, and nail problems, affecting patients' lives and requiring careful management.
[object Object] 12 citations,
April 2018 in “Revista Brasileira de Ginecologia e Obstetrícia” Women with Systemic Lupus Erythematosus should have closely monitored pregnancies and avoid certain medications to improve their pregnancy outcomes.
215 citations,
March 2011 in “Clinical Cancer Research” Sorafenib is effective in treating Desmoid Tumor/Deep Fibromatosis.
78 citations,
February 2011 in “Canadian Medical Association Journal” Acne treatment varies, with topical and systemic therapies effective, and more research needed on treatment order and long-term effects.
36 citations,
June 2017 in “Journal of Cutaneous Medicine and Surgery” The consensus document recommends a comprehensive treatment plan for Hidradenitis Suppurativa, including various medications, surgery, lifestyle changes, and the need for more research and resources.
August 2001 in “Journal of Cutaneous Medicine and Surgery” Prednisone has risks for lupus patients, isotretinoin is safe for mental health, transplant patients risk skin cancer, and various treatments are effective for specific skin conditions.
82 citations,
January 2000 in “Hormone Research in Paediatrics” DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.
47 citations,
August 2000 in “Endocrine Reviews” The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.
14 citations,
April 2014 in “Medical Clinics of North America” The document concludes that quick referral and appropriate treatments are crucial for managing common skin conditions and preventing permanent damage.
1 citations,
January 2001 in “Endocrine Practice” Topical finasteride may help treat facial hirsutism in women.
May 2022 in “Journal of the Egyptian Women's Dermatologic Society (Print)” Women's hair loss can be due to hormonal changes and various conditions, with treatments focusing on stopping progression and managing symptoms.
July 2021 in “British Journal of Dermatology” A woman with systemic sclerosis developed a unique scarring hair loss combining features of systemic sclerosis and frontal fibrosing alopecia.
20 citations,
December 1995 in “International Journal of Pharmaceutics” Liposomes can make the antiandrogen RU 58841 more effective for skin application by reducing absorption, increasing skin retention, and targeting sebaceous structures.
237 citations,
December 2001 in “Urology” Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.
41 citations,
March 1998 in “Archives of Dermatological Research” The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.
9 citations,
January 2017 in “Organic Process Research & Development” In 2017, a new method was created to efficiently produce a topical antiandrogen, a compound used to treat excess sebum and acne, with a high yield and purity.
6 citations,
March 2019 in “International Journal of Molecular Medicine” Finasteride microspheres help reduce hair loss for up to eight weeks with fewer side effects.
1 citations,
July 2021 in “Clinical and Experimental Dermatology” Finasteride helps reduce hidradenitis suppurativa symptoms in females.
38 citations,
October 1996 in “Dermatologic Clinics” Certain hormone treatments can improve acne and related conditions in women.
26 citations,
June 2016 in “Journal of Reproductive Immunology” Women with PCOS have higher xanthine oxidase activity linked to inflammation and heart disease risks.
29 citations,
February 2007 in “Hormone and metabolic research” Blocking the androgen receptor in skin cells reduces their growth response to male hormones, suggesting a possible treatment for skin conditions linked to androgens.