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    Glossary Sweat Glands

    small skin structures producing sweat for temperature regulation

    Sweat glands, also known as sudoriferous glands, are small tubular structures in the skin responsible for producing sweat. They play a crucial role in regulating body temperature and excreting waste products. There are two main types: eccrine glands, which are found all over the body and primarily help with cooling, and apocrine glands, which are located in specific areas like the armpits and groin and are associated with body odor.

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    1. Identification of Stem Cell Populations in Sweat Glands and Ducts Reveals Roles in Homeostasis and Wound Repair Cell · 2012 · 265 citations
    2. Human Eccrine Sweat Gland Cells Can Reconstitute a Stratified Epidermis Journal of Investigative Dermatology · 2010 · 103 citations
    3. Histochemical and Immunohistochemical Markers for Human Eccrine and Apocrine Sweat Glands: An Aid for Histopathologic Differentiation of Sweat Gland Tumors Journal of Investigative Dermatology Symposium Proceedings · 2001 · 73 citations
    4. Using bioprinting and spheroid culture to create a skin model with sweat glands and hair follicles Burns & Trauma · 2021 · 65 citations
    5. Involvement of Wnt, Eda and Shh at defined stages of sweat gland development Development · 2014 · 55 citations
    6. Label Retaining Cells (LRCs) with Myoepithelial Characteristic from the Proximal Acinar Region Define Stem Cells in the Sweat Gland PLoS ONE · 2013 · 36 citations
    7. The secretory clear cell of the eccrine sweat gland as the probable source of excess sweat production in hyperhidrosis Experimental Dermatology · 2011 · 36 citations
    8. Multipotent Nestin-Positive Stem Cells Reside in the Stroma of Human Eccrine and Apocrine Sweat Glands and Can Be Propagated Robustly In Vitro PloS one · 2013 · 33 citations
    9. Isolation and Characterization of Sweat Gland Myoepithelial Cells from Human Skin Cell Structure and Function · 2014 · 26 citations
    10. Reflectance confocal microscopy can differentiate dermoscopic white dots of the scalp between sweat gland ducts or follicular infundibulum British Journal of Dermatology · 2011 · 20 citations
    11. Characterization of X‐linked hypohidrotic ectodermal dysplasia (XL‐HED) hair and sweat gland phenotypes using phototrichogram analysis and live confocal imaging American Journal of Medical Genetics - Part A · 2013 · 15 citations
    12. Trichoblastoma with sebaceous and sweat gland differentiation 2001 · 12 citations
    13. The protease corin regulates electrolyte homeostasis in eccrine sweat glands PLoS biology · 2021 · 10 citations
    14. Small molecules facilitate single factor-mediated sweat gland cell reprogramming Military Medical Research · 2022 · 9 citations
    15. VEGFR-2 Is in a State of Activation in Hair Follicles, Sebaceous Glands, Eccrine Sweat Glands, and Epidermis from Human Scalp: An In Situ Immunohistochemistry Study of Phosphorylated VEGFR-2 2019 · 6 citations
    16. The combination of hair follicle-specific marker LHX2 and co-expressed marker can distinguish between sweat gland placodes and hair placodes in rat Journal of Molecular Histology · 2021 · 5 citations
    17. Collagen triple helix repeat containing-1 promotes functional recovery of sweat glands by inducing adjacent microvascular network reconstruction <i>in vivo</i> Burns & Trauma · 2022 · 3 citations
    18. A transient dermal niche and dual epidermal programs underlie sweat gland development bioRxiv (Cold Spring Harbor Laboratory) · 2023
    19. Commentary on Elimination of Sweat Glands Using the Follicular Unit Excision Technique Dermatologic Surgery · 2021
    20. 250 Sweat glands shrink upward with aging, causing dermal layer defects that lead to loss of skin elasticity and wrinkling-establishment of 3D imaging method for skin appendages Journal of Investigative Dermatology · 2017
    21. 259 Immunohistochemical insight into the association between the collapse of immune privilege in the sweat gland and syringotropic immune cell infiltrates in collagen diseases Journal of Investigative Dermatology · 2017
    22. Morphological and distribution characteristics of sweat glands in hypertrophic scar and their possible effects on sweat gland regeneration 中华医学杂志:英文版 · 2005
    23. 0932 Spatiotemporal gradient of mesenchymal stiffness controls sweat gland morphogenesis Journal of Investigative Dermatology · 2026
    24. 439 Gradients of Mesenchymal Stiffness Control Sweat Gland Cell Fate Specification During Morphogenesis Journal of Investigative Dermatology · 2025
    25. Culture Strategy Determines the Differentiation Status of Sweat Gland Cells Cells · 2025
    26. From the Microscopic Sweat Gland to Large Datasets: The Power of Quantitative Traits in Dermatology Journal of Investigative Dermatology · 2024
    27. Immunohistochemical staining characteristics of epidermal appendages (hair follicles and eccrine sweat glands) to anti-epidermal keratin antisera Acta Dermato Venereologica · 1984 · 6 citations
    28. Eccrine sweat glands associate with the human hair follicle within a defined compartment of dermal white adipose tissue British Journal of Dermatology · 2018 · 36 citations
    29. K31 as a novel marker for clear secretory cells in human eccrine sweat glands Journal of Molecular Histology · 2020 · 32 citations
    30. Reduced cell cohesiveness of outgrowths from eccrine sweat glands delays wound closure in elderly skin Aging Cell · 2016 · 19 citations