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The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

Finasteride doesn't effectively treat hair loss in postmenopausal women.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

The document provides a method to classify human hair growth stages using a model with human scalp on mice, aiming to standardize hair research.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

Hair loss in men is common, treatable, but not curable.

Erectile dysfunction is increasingly common in men under 40, with many physical and psychological causes, and various treatment options available.

Oestrogens are key for bone growth during puberty in both boys and girls.

Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.

Myrtle has various health benefits and potential for medicine development.

The peptide GHK-Cu helps heal and remodel tissue, improves skin and hair health, and has potential for treating age-related inflammatory diseases.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

PRP injections increase hair density and satisfaction in androgenetic alopecia patients.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Tributyltin exposure causes sex changes, sterilization, and decline in the snail Ocinebrina aciculata, risking its extinction.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Estrogen therapy can reduce skin aging but has cancer risks.

Too much androgen can cause hair loss; finasteride may help.

Dextran sulfate was found to be toxic and ineffective for treating HIV.

Modern science supports the use of some Ayurvedic plants for health, as ancient practices suggested.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Men's sensitivity to male hormones might affect how severe COVID-19 gets for them.

Finasteride exposure in pregnancy causes genital abnormalities in male rats.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Platelet-rich plasma might help with hair growth and skin conditions, but more research is needed to prove its effectiveness and safety.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.