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    Did you mean Steroid Metabolism?
    Glossary Steroid Metabolism

    process of breaking down and converting steroid hormones

    Steroid metabolism refers to the process by which the body breaks down and converts steroid hormones, such as cortisol, testosterone, and estrogen, into other substances. This involves a series of biochemical reactions primarily in the liver, where enzymes modify the steroid molecules to make them more water-soluble, allowing for their excretion through urine or bile. Understanding steroid metabolism is crucial for both diagnosing and treating conditions related to hormone imbalances and for the development of steroid-based medications.

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    Research 30 of 1000+

    1. OR20-01 Machine Learning-based Steroid Metabolome Analysis In Women With Polycystic Ovary Syndrome Reveals Three Distinct Androgen Excess Subtypes With Different Metabolic Risk Profiles. Journal of the Endocrine Society · 2023
    2. Untargeted metabolomics and steroid signatures in urine of male pattern baldness patients after finasteride treatment for a year Zenodo (CERN European Organization for Nuclear Research) · 2020
    3. Untargeted Metabolomics and Steroid Signatures in Urine of Male Pattern Baldness Patients after Finasteride Treatment for a Year Metabolites · 2020 · 8 citations
    4. Untargeted metabolomics and steroid signatures in urine of male pattern baldness patients after finasteride treatment for a year Zenodo (CERN European Organization for Nuclear Research) · 2020
    5. 28108 Untargeted metabolomics and steroid signatures in urine of male pattern baldness patients after finasteride treatment for a year Journal of The American Academy of Dermatology · 2021
    6. Urinary steroid metabolome shows adrenal, gonadal, and neuroactive steroid dysregulation in adolescents with depression 2025 · 1 citations
    7. Effects of sex steroid hormones and their metabolites on neuronal injury caused by oxygen-glucose deprivation/reoxygenation in organotypic hippocampal slice cultures Steroids · 2016 · 24 citations
    8. Machine learning-based steroid metabolome analysis reveals three distinct subtypes of polycystic ovary syndrome and implicates 11-oxygenated androgens as major drivers of metabolic risk Endocrine Abstracts · 2023 · 3 citations
    9. Hyperandrogenism, Elevated 17-Hydroxyprogesterone and Its Urinary Metabolites in a Young Woman with Ovarian Steroid Cell Tumor, Not Otherwise Specified: Case Report and Review of the Literature Case reports in endocrinology · 2019 · 7 citations
    10. 11α-Hydroxyprogesterone, a potent 11β-hydroxysteroid dehydrogenase inhibitor, is metabolised by steroid-5α-reductase and cytochrome P450 17α-hydroxylase/17,20-lyase to produce C11α-derivatives of 21-deoxycortisol and 11-hydroxyandrostenedione in vitro The Journal of Steroid Biochemistry and Molecular Biology · 2019 · 7 citations
    11. Sex Steroids, Precursors, and Metabolite Deficiencies in Men With Isolated Hypogonadotropic Hypogonadism and Panhypopituitarism: A GCMS-Based Comparative Study The Journal of Clinical Endocrinology & Metabolism · 2014 · 46 citations
    12. Doping-Control Analysis of the 5α-Reductase Inhibitor Finasteride: Determination of Its Influence on Urinary Steroid Profiles and Detection of Its Major Urinary Metabolite Therapeutic Drug Monitoring · 2007 · 39 citations
    13. Integrative Analysis of the Metabolome and Transcriptome Reveals the Mechanism Underlying Differences in Skin Development Between the New Zealand Rabbit and the Rex Rabbit Animals · 2026
    14. Testosterone metabolite nonessential for androgen effects Nature Reviews Endocrinology · 2012 · 2 citations
    15. Bioactive metabolites of edible mushrooms efficacious against androgenic alopecia: Targeting SRD5A2 using computational approach Journal of Herbal Medicine · 2022
    16. Bioactive metabolites of edible mushrooms efficacious against androgenic alopecia: Targeting SRD5A2 using computational approach Research Square (Research Square) · 2022
    17. Alterations in Pattern Baldness According to Sex: Hair Metabolomics Approach Metabolites · 2021 · 3 citations
    18. Urinary steroids in men with male-pattern alopecia Journal of Biochemical and Biophysical Methods · 2002 · 13 citations
    19. Urinary steroid analysis of women with effluvium Chromatographia · 1998
    20. Assessment of Circulating Sex Steroid Levels in Prepubertal and Pubertal Boys and Girls by a Novel Ultrasensitive Gas Chromatography-Tandem Mass Spectrometry Method The Journal of Clinical Endocrinology & Metabolism · 2009 · 169 citations
    21. Serum Metabolomics Study of Polycystic Ovary Syndrome Based on Liquid Chromatography–Mass Spectrometry Journal of Proteome Research · 2014 · 71 citations
    22. Neuroactive steroids inhibit spinal reflex potentiation by selectively enhancing specific spinal GABAA receptor subtypes Pain · 2009 · 44 citations
    23. Investigation Into the Metabolism and Elimination Behavior of RU 58841, and Its Influence on the Steroid Profile in Humans Biomedical Chromatography · 2026
    24. Identification of Metabolites for the Novel 5α‐Reductase Inhibitor Epristeride In Vitro and Its Potential Impact on Doping Testing Drug Testing and Analysis · 2025
    25. Geographic Influence and Metabolomics-Driven Discovery of 5-Alpha Reductase Inhibitors in Tectona grandis L.f. (Teak) Leaves Molecules · 2025
    26. Urinary 5-ene-steroid excretion in non-classical congenital adrenal hyperplasia due to 3β-hydroxysteroid dehydrogenase deficiency (NC-3BHSD) Journal of Steroid Biochemistry · 1990 · 3 citations
    27. Androgenic effect of testosterone and some of its metabolites in relation to their biotransformation in the skin. 1982 · 11 citations
    28. Synthesis and Actions of 5α-Reduced Metabolites of Testosterone in the Nervous System Androgens · 2021 · 1 citations
    29. Sexually dimorphic effect of progesterone and its reduced metabolites on the gene expression of myelin proteins in rat Schwann cells Frontiers in Neuroendocrinology · 2006
    30. Intracrine androgen biosynthesis, metabolism and action revisited Molecular and Cellular Endocrinology · 2017 · 131 citations