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    Did you mean Steroid Metabolism?
    Glossary Steroid Metabolism

    process of breaking down and converting steroid hormones

    Steroid metabolism refers to the process by which the body breaks down and converts steroid hormones, such as cortisol, testosterone, and estrogen, into other substances. This involves a series of biochemical reactions primarily in the liver, where enzymes modify the steroid molecules to make them more water-soluble, allowing for their excretion through urine or bile. Understanding steroid metabolism is crucial for both diagnosing and treating conditions related to hormone imbalances and for the development of steroid-based medications.

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    Research 30 of 1000+

    1. Effects of sex steroid hormones and their metabolites on neuronal injury caused by oxygen-glucose deprivation/reoxygenation in organotypic hippocampal slice cultures Steroids · 2016 · 24 citations
    2. Hyperandrogenism, Elevated 17-Hydroxyprogesterone and Its Urinary Metabolites in a Young Woman with Ovarian Steroid Cell Tumor, Not Otherwise Specified: Case Report and Review of the Literature Case reports in endocrinology · 2019 · 7 citations
    3. 11α-Hydroxyprogesterone, a potent 11β-hydroxysteroid dehydrogenase inhibitor, is metabolised by steroid-5α-reductase and cytochrome P450 17α-hydroxylase/17,20-lyase to produce C11α-derivatives of 21-deoxycortisol and 11-hydroxyandrostenedione in vitro The Journal of Steroid Biochemistry and Molecular Biology · 2019 · 7 citations
    4. Sex Steroids, Precursors, and Metabolite Deficiencies in Men With Isolated Hypogonadotropic Hypogonadism and Panhypopituitarism: A GCMS-Based Comparative Study The Journal of Clinical Endocrinology & Metabolism · 2014 · 46 citations
    5. Doping-Control Analysis of the 5α-Reductase Inhibitor Finasteride: Determination of Its Influence on Urinary Steroid Profiles and Detection of Its Major Urinary Metabolite Therapeutic Drug Monitoring · 2007 · 39 citations
    6. Bioactive metabolites of edible mushrooms efficacious against androgenic alopecia: Targeting SRD5A2 using computational approach Journal of Herbal Medicine · 2022
    7. Bioactive metabolites of edible mushrooms efficacious against androgenic alopecia: Targeting SRD5A2 using computational approach Research Square (Research Square) · 2022
    8. Testosterone metabolite nonessential for androgen effects Nature Reviews Endocrinology · 2012 · 2 citations
    9. Urinary steroids in men with male-pattern alopecia Journal of Biochemical and Biophysical Methods · 2002 · 13 citations
    10. Urinary steroid analysis of women with effluvium Chromatographia · 1998
    11. Assessment of Circulating Sex Steroid Levels in Prepubertal and Pubertal Boys and Girls by a Novel Ultrasensitive Gas Chromatography-Tandem Mass Spectrometry Method The Journal of Clinical Endocrinology & Metabolism · 2009 · 169 citations
    12. Neuroactive steroids inhibit spinal reflex potentiation by selectively enhancing specific spinal GABAA receptor subtypes Pain · 2009 · 44 citations
    13. Investigation Into the Metabolism and Elimination Behavior of RU 58841, and Its Influence on the Steroid Profile in Humans Biomedical Chromatography · 2026
    14. Identification of Metabolites for the Novel 5α‐Reductase Inhibitor Epristeride In Vitro and Its Potential Impact on Doping Testing Drug Testing and Analysis · 2025
    15. Urinary 5-ene-steroid excretion in non-classical congenital adrenal hyperplasia due to 3β-hydroxysteroid dehydrogenase deficiency (NC-3BHSD) Journal of Steroid Biochemistry · 1990 · 3 citations
    16. Androgenic effect of testosterone and some of its metabolites in relation to their biotransformation in the skin. 1982 · 11 citations
    17. Synthesis and Actions of 5α-Reduced Metabolites of Testosterone in the Nervous System Androgens · 2021 · 1 citations
    18. Sexually dimorphic effect of progesterone and its reduced metabolites on the gene expression of myelin proteins in rat Schwann cells Frontiers in Neuroendocrinology · 2006
    19. Rare and common genetic determinants of metabolic individuality and their effects on human health Nature Medicine · 2022 · 29 citations
    20. A randomized placebo-controlled study on the effects of pioglitazone on cortisol metabolism in polycystic ovary syndrome Fertility and sterility · 2008 · 24 citations
    21. Influence of finasteride treatment on metabolic profile of men with androgenetic alopecia 11th European Congress of Endocrinology · 2009
    22. Intracrine androgen biosynthesis, metabolism and action revisited Molecular and Cellular Endocrinology · 2017 · 131 citations
    23. Integrative Analysis of the Metabolome and Transcriptome Reveals the Mechanism Underlying Differences in Skin Development Between the New Zealand Rabbit and the Rex Rabbit Animals · 2026
    24. A Teenage Girl with Unexpected Pubertal Changes Clinical chemistry · 2018 · 1 citations
    25. Sulfotransferases, sulfatases and formylglycine-generating enzymes: a sulfation fascination Current Opinion in Chemical Biology · 2008 · 83 citations
    26. Evidence for Increased 5α-Reductase Activity During Early Childhood in Daughters of Women With Polycystic Ovary Syndrome The Journal of Clinical Endocrinology & Metabolism · 2016 · 40 citations
    27. Steroidomics for highlighting novel serum biomarkers of testosterone doping Bioanalysis · 2019 · 23 citations
    28. Long-term detection of methyltestosterone (ab-) use by a yeast transactivation system Archives of Toxicology · 2010 · 15 citations
    29. Lactiplantibacillus plantarum ZJUIDS51 improves androgenic alopecia via gut-skin axis Food Research International · 2026
    30. Untargeted metabolomics and steroid signatures in urine of male pattern baldness patients after finasteride treatment for a year Zenodo (CERN European Organization for Nuclear Research) · 2020