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The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

Spironolactone treatment increases the amount of testosterone available in the body.

Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

The document concludes that the fast-growing direct-to-consumer genetic testing market lacks sufficient regulation, posing risks to consumers due to questionable test quality and accuracy.

Middle-aged women with chronic telogen effluvium experience increased hair shedding but usually don't get significantly thinner hair.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Hair loss affects women's mental health more than men's, causing anxiety, low self-esteem, and social insecurity.

Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.

Testing basal 17-HP levels is a good way to screen for nonclassic adrenal hyperplasia in women with high androgen levels.

Sorafenib is effective in treating Desmoid Tumor/Deep Fibromatosis.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

MK-0773 safely increased muscle mass but did not improve muscle strength or function in elderly women with sarcopenia.

Stem cell niches are crucial for regulating stem cell renewal and differentiation, and understanding them can help in developing regenerative therapies.

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.

Hair follicle development and microbes help regulatory T cells gather in newborn skin.

Hair loss can cause low self-esteem, anxiety, and depression in men.

Researchers found 19 genes important for root hair growth in a plant called Arabidopsis.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Oral antiandrogens effectively treat female hair loss, with better results in higher hair loss grades.

The conclusion is that accurate diagnosis of different types of hair loss requires good teamwork between skin doctors and lab experts.

Some people with pattern hair loss may also have scalp inflammation and scarring similar to lichen planopilaris.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Dermatoscopy and videodermatoscopy are useful for diagnosing and monitoring various skin, hair, and nail conditions.

Accurate diagnosis and effective oral treatment are key to managing tinea capitis and preventing its spread.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

Male pattern baldness involves genetics, hormones, and needs better treatments.

Follicular Unit Extraction (FUE) is a less invasive hair transplant method with minimal scarring, suitable for about 60% of patients, especially those needing fewer grafts and quicker recovery.