November 2023 in “JEADV Clinical Practice” In this study, adults with severe alopecia areata experienced greater improvements in hair regrowth, health-related quality of life, and reduced anxiety and depression symptoms after 36 weeks of treatment with baricitinib compared to placebo.
This study found that androgenic alopecia significantly impaired quality of life among men in the Eastern Province of Saudi Arabia, with younger males and those diagnosed by a doctor experiencing greater quality of life issues, particularly in the symptoms domain.
August 2023 in “International Journal of Women's Dermatology” In this study, a case of a 70-year-old woman with central centrifugal cicatricial alopecia showed that using a high-quality hair prosthesis improved her quality of life and mood, as measured by PHQ-9 and Skindex-29 scores, though such wigs are rarely covered by insurance.
This study found that low-intensity light therapy improved quality of life related to emotional, psychosocial, and symptom domains in individuals with androgenic alopecia, with a greater impact observed in women.
April 2018 in “Journal of Investigative Dermatology” This study suggests that for dermatomyositis patients with minimal skin disease activity, further improvement in cutaneous symptoms may not translate into better quality of life, highlighting a need to revise trial endpoints.
September 2016 in “Annals of occupational and environmental medicine” In this study, cleanroom workers in a secondary battery factory reported worse dermatologic life quality compared to non-cleanroom workers, as measured by the Skindex-29 questionnaire.
April 2016 in “Journal of The American Academy of Dermatology” AGA patients have a lower quality of life than AA patients.
101 citations
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January 2012 in “Annals of Dermatology” In this study, researchers found that androgenetic alopecia significantly harms quality of life, particularly in younger patients, those with more severe or long-term alopecia, and those who have sought non-medical hair care.
15 citations
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January 2018 in “Annals of Dermatology” Wigs significantly improve the well-being of people with severe hair loss.
This study found that 49% of female breast cancer patients treated with CDK4/6 inhibitors for at least three months developed alopecia, which significantly impacted their quality of life, with greater alopecia severity leading to worse emotional and functional well-being.
April 2022 in “Journal of the Medical Sciences” This study found a significant relationship between the severity of androgenetic alopecia in men and a negative impact on their quality of life.
December 2021 in “Journal of BP Koirala Institute of Health Sciences” This study found that male patients with androgenetic alopecia experienced more emotional impact than symptomatic or functional effects, highlighting the importance of assessing quality of life in these individuals.
March 2021 in “Journal of The European Academy of Dermatology and Venereology” Low quality of life and high HSS-29 scores increase risk of losing patients during treatment.
In this clinical trial, patients with lichen planopilaris treated with the oral TYK2 inhibitor deucravacitinib showed significant improvement in PGA, LPPAI, and Skindex-16 scores over 24 weeks, with transcriptomic analyses indicating decreased inflammatory and immune pathway activity post-treatment.
December 2013 in “Praxis medica” In this study, a strong correlation was found between the scores of two dermatology-specific quality of life instruments, DLQI and Skindex-16, suggesting they can provide complementary insights for assessing patients with skin diseases.
This summary highlights key contents of the latest issue of the Austrian dermatology journal, SKIN, including coverage of the ÖADF conference program, introduction of a "Phlebology Certificate," and new SKINdeep open-access articles.
18 citations
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November 2000 in “British Journal of Dermatology” This study reports that over one-quarter of dermatology outpatients show psychiatric morbidity, highlighting the importance of considering psychological factors in managing skin diseases.
17 citations
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June 2024 in “Journal of the European Academy of Dermatology and Venereology” This study suggests that using an appropriate tool for measuring quality of life is vital, particularly as factors like severity, female sex, and eyebrow involvement may increase the psychosocial burden of alopecia areata.
4 citations
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December 2020 in “Neuropsychiatric Disease and Treatment” In this study, body dysmorphic disorder symptoms in dermatological patients were strongly linked to psychiatric issues and reduced quality of life, particularly among those with unclassified dermatoses.
1 citations
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November 2024 in “Journal of Investigative Dermatology” Er:YAG laser therapy effectively treats Hailey-Hailey disease, leading to long-term remission and improved quality of life.
August 2026 in “Russian Journal of Skin and Venereal Diseases” In this prospective study, combining photodynamic therapy with PRP therapy significantly improved hair growth, quality of hair, and quality of life in women with acute telogen effluvium, compared to using each therapy alone.
November 2025 in “Journal of Clinical Medicine” The researchers reported that baricitinib treatment for at least 52 weeks reduced severe alopecia areata severity and improved psychological well-being and quality of life in study participants.
September 2025 in “Journal of the European Academy of Dermatology and Venereology” This real-world study found that baricitinib 4 mg daily was effective in promoting hair regrowth and improving psychological well-being in Italian adults with severe alopecia areata over 48 weeks, with 63.2% of patients achieving significant hair recovery and 9.4% experiencing adverse events.
December 2025 in “SKINdeep” This paper reviews existing studies on the role of environmental humidity in skin health, highlighting that low humidity can impair the skin's barrier function and trigger inflammatory responses, though the precise mechanisms remain to be fully explored.
September 2025 in “SKINdeep” This study highlights the positive roles of sebaceous glands in skin health, including lubrication of hair follicles, delivery of antimicrobial lipids and vitamin E, and involvement in vitamin D conversion, contrasting their traditional association with skin conditions like acne.
June 2026 in “BMC Microbiology” In this study, researchers demonstrated that using cyanoacrylate glue effectively reduces microbial contamination in biopsy samples from the skin surface of wild roe deer, offering valuable insights for human hair follicle microbiome research despite the nonhuman model.
1 citations
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April 2016 in “Journal of The American Academy of Dermatology” This study found that patients with androgenetic alopecia experienced more severe symptoms than those with alopecia areata, influencing their quality of life differently based on various patient characteristics.
April 2016 in “Journal of The American Academy of Dermatology” This study found that patients with androgenetic alopecia had higher symptom-related quality of life impairment than those with alopecia areata, with specific influences from age, disease duration, and severity.
8 citations
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October 2018 in “Journal of Investigative Dermatology” This study observed that alopecia areata patients experience significant psychosocial issues, with a high prevalence of anxiety, depression, and impaired quality of life across symptoms, functioning, and emotions.
March 2026 in “Dermatology and Therapy” In this study, researchers found that patients with severe alopecia areata often experience reduced health-related quality of life, with significant levels of anxiety and depression, and these mental health impacts may correlate with the severity of their condition.