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    Glossary Skin Penetration

    process by which substances pass through the outer skin layer

    Skin penetration refers to the process by which substances pass through the outermost layer of the skin, known as the stratum corneum, to reach deeper layers. This is a critical concept in dermatology and pharmacology, as it influences the effectiveness of topical medications and skincare products. Factors such as molecular size, solubility, and the condition of the skin can affect how well a substance penetrates.

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    1. Penetration of drugs through skin, a complex rate-controlling membrane 2012 · 211 citations
    2. Measurement of Skin Permeation/Penetration of Nanoparticles for Their Safety Evaluation Biological and Pharmaceutical Bulletin · 2012 · 67 citations
    3. Cyproterone acetate-loaded nanostructured lipid carriers: effect of particle size on skin penetration and follicular targeting Pharmaceutical development and technology · 2019 · 40 citations
    4. Nobiletin-loaded composite penetration enhancer vesicles restore the normal miRNA expression and the chief defence antioxidant levels in skin cancer Scientific Reports · 2021 · 34 citations
    5. Skin Penetration and Permeation Properties of Transcutol® in Complex Formulations AAPS PharmSciTech · 2024 · 29 citations
    6. Comparison of the skin penetration of Garcinia mangostana extract in particulate and non-particulate form European journal of pharmaceutics and biopharmaceutics · 2013 · 19 citations
    7. Film-trigger applicator (FTA) for improved skin penetration of microneedle using punching force of carboxymethyl cellulose film acting as a microneedle applicator Biomaterials Research · 2022 · 17 citations
    8. Germacrone and sesquiterpene-enriched extracts from Curcuma aeruginosa Roxb. increase skin penetration of minoxidil, a hair growth promoter Drug Delivery and Translational Research · 2017 · 15 citations
    9. Enhanced skin penetration of lidocaine through encapsulation into nanoethosomes and nanostructured lipid carriers: a comparative study ˜Die œPharmazie · 2016 · 15 citations
    10. Novel iron oxide nanocarriers loading finasteride or dutasteride: Enhanced skin penetration for topical treatment of alopecia International Journal of Pharmaceutics · 2020 · 12 citations
    11. Oil Body-Bound Oleosin-rhFGF-10: A Novel Drug Delivery System that Improves Skin Penetration to Accelerate Wound Healing and Hair Growth in Mice International Journal of Molecular Sciences · 2017 · 11 citations
    12. Effect of Charge Carrier Lipid on Skin Penetration, Retention, and Hair Growth of Topically Applied Finasteride-Containing Liposomes Biomolecules & Therapeutics · 2011 · 11 citations
    13. Evaluation of Skin Penetration of Fluorescent Dissolved Formulations Using Confocal Laser Scanning Microscopy Pharmaceutics · 2025 · 2 citations
    14. Skin penetration of active folate salts and their effects on wound healing in vitro: new approaches for dermal folate application 2023 · 1 citations
    15. Development and Skin Penetration Pathway Evaluation Using Confocal Laser Scanning Microscopy of Microemulsions for Dermal Delivery Enhancement of Finasteride Pharmaceutics · 2022 · 1 citations
    16. High spatial resolution study of human skin using synchrotron infrared microscopy: application to the penetration of external agents International Journal of Cosmetic Science · 2004 · 1 citations
    17. Skin Penetration of Caffeine and Cafestol using Liposomes: Exploring the Benefits of a Combined Delivery System AAPS PharmSciTech · 2026
    18. P62 Pre-clinical pharmacological and skin penetration profile of LDE255, a novel and specific Smoothened antagonist Melanoma research · 2010
    19. Follicular Penetration of Caffeine from Topically Applied Nanoemulsion Formulations Containing Penetration Enhancers: In vitro Human Skin Studies Skin pharmacology and physiology · 2018 · 35 citations
    20. Solvent-Containing Closure Material Can Be Used to Prevent Follicular Penetration of Caffeine and Fluorescein Sodium Salt on Porcine Ear Skin Skin Pharmacology and Physiology · 2020 · 7 citations
    21. Penetration and storage of particles in human skin: Perspectives and safety aspects European Journal of Pharmaceutics and Biopharmaceutics · 2011 · 122 citations
    22. Penetration and Local Effect of Vitamin A on the Skin of the Guinea Pig., Experimental Biology and Medicine · 1954 · 45 citations
    23. Somatotropin Penetration Testing from Formulations Applied Topically to the Skin Applied sciences · 2023 · 1 citations
    24. Penetration and Distribution in Human Skin Focusing on the Hair Follicle Drugs and the pharmaceutical sciences · 2005 · 1 citations
    25. Penetration and Distribution in Human Skin Focusing on the Hair Follicle CRC Press eBooks · 2005 · 1 citations
    26. Follicular penetration of nano-sized particulate FA-PLGA and the dye RhBITC in dorsal dog and rat skin, and porcine ear skin as an in vitro model for the human integument 2011
    27. IMPROVED SKIN PENETRATION AND DEPOSITION OF NAFTIFINE FROM TRANSETHOSOMES AND TRANSETHOSOMAL GEL FORMULATIONS FARMACIA · 2022 · 12 citations
    28. Enhanced Follicular Delivery of Finasteride to Human Scalp Skin Using Heat and Chemical Penetration Enhancers Pharmaceutical Research · 2020 · 5 citations
    29. Mechanistic study of decreased skin penetration using a combination of sonophoresis with sodium fluorescein-loaded PEGylated liposomes with D-limonene DOAJ (DOAJ: Directory of Open Access Journals) · 2015 · 2 citations
    30. Enhanced skin penetration of Finasteride loaded DMSO-liposomes for the treatment of androgenic alopecia: comparison with conventional liposomes Drug Development and Industrial Pharmacy · 2023 · 1 citations