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Testosterone can build muscle and bone without enlarging the prostate when a specific enzyme is blocked.

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.

Gene therapy shows promise for enhancing physical traits but faces ethical, safety, and regulatory challenges.

Vismodegib is effective for basal cell carcinoma but has severe side effects.

Androgen therapy can help with symptoms like low libido in women, but more research is needed to understand its long-term safety and effects on health.

Gender-affirming hormone therapy improves physical performance in trans men to the level of cisgender men, while in trans women, it increases fat mass and decreases muscle mass, with no advantage in physical performance after 2 years.

SLVs help maintain muscle stretch sensitivity and could aid in treating hypertension and muscle spasticity.

Glucocorticoids for progressive muscular dystrophy in children don't improve muscle strength or function but do increase certain side effects.

Early diagnosis and treatment of TPP can prevent complications.

A compound named ZCZ90 can increase muscle spindle firing, potentially helping treat muscle spasms and hypertension.

Neurotoxins can affect neurotransmitter release and have potential in treating muscle, pain, and cancer conditions, but more research is needed on how they work.

Many men misuse oral contraceptive pills for things like hair growth and muscle gain.

A new mutation in the PLEC gene causes a rare condition with skin blistering, muscle weakness, and hair loss.

Testosterone is important for male sexual traits, reproduction, muscle and bone health, blood production, and metabolism, and works both directly and after being changed into other hormones.

There is no cure for myotonic dystrophy type 1, so treatment focuses on managing symptoms and complications.

Potassium channel openers could help treat cardiovascular diseases and asthma but require better targeting to specific tissues for effective use.

Bolandiol, a synthetic steroid, builds muscle and bone without greatly affecting sex glands, and works differently from other hormones.

A specific gene variant is linked to heart disease, increased heart muscle, curly hair, and thick skin on palms and soles.

Alopecia is a key indicator of thallium poisoning.

The tumor suppressor gene FLCN affects mitochondrial function and energy use in cells.

Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

Pannexin 3 is important for bone formation and the development of bone cells.

Researchers created a mouse model for Cushing's syndrome to study glucocorticoid excess and potential treatments.

Men need higher doses and tailored injection techniques for botulinum toxin treatments due to their unique facial features.

Eosinophilia-myalgia syndrome, linked to contaminated L-tryptophan supplements, caused severe symptoms and some deaths, with long-term effects in survivors.

Some supplements and hormones can increase hair loss by raising DHT levels.

A genetic region near the PAX1 gene is linked to a higher risk of scoliosis in females.

Male hormones, or androgens, affect women's health in areas like mood and bone density, and hormone replacement therapy using antiandrogenic progestogens can improve mood disorders and alertness in menopausal women.

Astaxanthin is a safe antioxidant that may improve heart, skin, eye health, and physical performance, and help manage chronic diseases.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.