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Mast cells play a significant role in hair loss conditions like male pattern hair loss and alopecia areata.

Acidic sandy clay damages archaeological hair the most, while dry conditions preserve but make it brittle; silicone oil can help keep the hair flexible.

Insulin resistance is linked to PCOS and can lead to other health issues, but treatments like metformin can help manage symptoms.

The document concludes that Syndromes of Severe Insulin Resistance are rare disorders with limited treatment options.

International medical graduates scored higher than U.S. graduates on a medical exam.

In 1995, international medical graduates did better than U.S. graduates on a medical exam.

Human skin can make serotonin and melatonin, which help protect and maintain it.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

New nanofiber technology improves wound healing by supporting cell growth and delivering treatments directly to the wound.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Dermatologists need to understand hair products to treat hair and scalp issues better.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Dermatoscopy and videodermatoscopy are useful for diagnosing and monitoring various skin, hair, and nail conditions.

Male pattern baldness involves genetics, hormones, and needs better treatments.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Effective treatments for male pattern baldness include oral finasteride and topical minoxidil, while topical minoxidil is best for female pattern baldness.

Alopecia areata causes hair loss, has no cure, and various treatments exist.

Silver can help prevent and treat infections but its effectiveness varies and should be weighed against costs and side effects.

Liposomes improve drug delivery and reduce skin irritation in dermatology.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Substances from Chinese medicines show promise for immune support and disease prevention, but the way they are processed affects their effectiveness.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.

Nerves and chemicals in the body can affect hair growth and loss.

New treatments for Alopecia Areata show promise but need to be more effective and affordable.