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      Alopecia Areata: An Autoimmune Disease Causing Hair Loss

      research Alopecia Areata

      421 citations , April 2012 in “The New England Journal of Medicine”
      Alopecia Areata is an autoimmune condition causing hair loss with no cure and treatments that often don't work well.
      The Neurobiology of Sexual Function

      research The Neurobiology of Sexual Function

      393 citations , November 2000 in “Archives of General Psychiatry”
      This review discusses the neurobiology of sexual function and reports no new results; the authors cover multiple endocrine and neurotransmitter influences on sexual desire, arousal, and orgasm stages.
      Alopecia Areata Update

      research Alopecia areata update

      391 citations , January 2010 in “Journal of The American Academy of Dermatology”
      This article reviews the clinical presentation and histopathologic features of alopecia areata and proposes a hypothesis for its development, but it reports no new clinical results.
      Treatment of Hair Loss

      research Treatment of Hair Loss

      370 citations , September 1999 in “The New England Journal of Medicine”
      This article discusses the treatment of androgenetic alopecia and alopecia areata with finasteride and minoxidil but reports no new clinical results.
      Sexual Hormones in Human Skin

      research Sexual Hormones in Human Skin

      305 citations , February 2007 in “Hormone and metabolic research”
      This review discusses the roles of androgens and estrogens in skin functions and disorders, and highlights the use of estrogen-progestin treatments and anti-androgens in managing hirsutism and acne, without reporting new results.
      Hirsutism

      research Hirsutism

      271 citations , December 2005 in “New England journal of medicine/˜The œNew England journal of medicine”
      This article discusses evaluation and treatment options for a 19-year-old woman with slowly progressive hair growth and reports no new clinical findings.
      Bioavailability of Albumin-Bound Testosterone

      research Bioavailability of Albumin-Bound Testosterone†

      255 citations , October 1985 in “The Journal of Clinical Endocrinology & Metabolism”
      This study concluded that albumin-bound testosterone is biologically important and significantly contributes to testosterone bioavailability in women receiving spironolactone.
      Teriflunomide and Its Mechanism of Action in Multiple Sclerosis

      research Teriflunomide and Its Mechanism of Action in Multiple Sclerosis

      253 citations , April 2014 in “Drugs”
      This review discusses the preclinical and clinical data on teriflunomide for multiple sclerosis, highlighting its selective action on immune cells without causing clinical immune suppression, and provides no new clinical results.
      Cutaneous Androgen Metabolism: Basic Research And Clinical Perspectives

      research Cutaneous Androgen Metabolism: Basic Research and Clinical Perspectives

      233 citations , November 2002 in “˜The œjournal of investigative dermatology/Journal of investigative dermatology”
      This review explores androgen metabolism in the skin, highlighting enzyme localization and potential implications for treating androgen-dependent skin conditions, but it reports no new clinical results.
      Wnt Signaling and Injury Repair

      research Wnt Signaling and Injury Repair

      232 citations , June 2012 in “Cold Spring Harbor Perspectives in Biology”
      This review summarizes the roles of Wnt signaling in wound healing but presents no new clinical findings, suggesting potential for Wnt-based therapies to enhance tissue regeneration.
      A Guide to Studying Human Hair Follicle Cycling In Vivo

      research A Guide to Studying Human Hair Follicle Cycling In Vivo

      212 citations , September 2015 in “Journal of Investigative Dermatology”
      This article presents a comprehensive guide for classifying human hair follicle cycle stages in vivo using scalp xenografts on immunocompromised mice, offering valuable resources for researchers in the field.
      Dermatoses of Pregnancy

      research Dermatoses of pregnancy

      208 citations , July 2001 in “Journal of The American Academy of Dermatology”
      This review discusses the classification and diagnosis of pregnancy-related skin conditions and reports no new clinical findings.
      Sebocytes Are the Key Regulators of Androgen Homeostasis in Human Skin

      research Sebocytes are the Key Regulators of Androgen Homeostasis in Human Skin

      196 citations , May 2001 in “˜The œjournal of investigative dermatology/Journal of investigative dermatology”
      This study found that SZ95 sebocytes and HaCaT keratinocytes exhibit distinct enzyme expressions and activities, implicating their different roles in androgen metabolism and homeostasis in vitro.
      The Evaluation and Management of Hirsutism

      research The evaluation and management of hirsutism*1

      195 citations , May 2003 in “Obstetrics and gynecology (New York. 1953. Online)/Obstetrics and gynecology”
      This review discusses the diagnosis and treatment of hirsutism, emphasizing that a systematic evaluation can determine its cause, while combination therapy effectively manages the condition for most patients.
      Alopecia Areata: A Review of Disease Pathogenesis

      research Alopecia areata: a review of disease pathogenesis

      191 citations , May 2018 in “British journal of dermatology/British journal of dermatology, Supplement”
      This study reviewed recent theories on alopecia areata's pathogenesis, highlighting its autoimmune nature due to immune privilege disruption in hair follicles, and noted current treatments have limited efficacy with high relapse rates, underscoring the need for further research into its mechanisms for better therapies.
      Herbal Therapy in Dermatology

      research Herbal Therapy in Dermatology

      191 citations , February 2002 in “Archives of Dermatology”
      This review discusses herbal therapies for dermatologic disorders, focusing on those with scientific evidence of efficacy and common interactions, but reports no new clinical results.
      Alopecia Areata Profiling Shows TH1, TH2, and IL-23 Cytokine Activation Without Parallel TH17/TH22 Skewing

      research Alopecia areata profiling shows TH1, TH2, and IL-23 cytokine activation without parallel TH17/TH22 skewing

      176 citations , August 2015 in “ˆThe ‰journal of allergy and clinical immunology/Journal of allergy and clinical immunology/˜The œjournal of allergy and clinical immunology”
      This study identified a distinct cytokine activation signature in alopecia areata, involving TH2, TH1, IL-23, and IL-9/TH9 pathways, suggesting potential targeting strategies similar to those in psoriasis and atopic dermatitis.
      Effects of Sex Steroid Deprivation and Administration on Hair Growth and Skin Sebum Production in Transsexual Males and Females

      research Effects of Sex Steroid Deprivation/Administration on Hair Growth and Skin Sebum Production in Transsexual Males and Females

      176 citations , August 2000 in “˜The œJournal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism”
      In this study, cross-sex hormone therapy affected hair growth patterns differently, with estrogen reducing hair growth in male-to-female transsexuals and testosterone increasing it in female-to-male transsexuals; however, male typical hair diameters were not fully reached in the latter group after 12 months.
      Clinical Manifestations of Toxic Shock Syndrome

      research Clinical Manifestations of Toxic Shock Syndrome

      176 citations , August 1981 in “JAMA”
      This study reported that toxic shock syndrome, originally noted in children, is now predominantly associated with menstruating women, with some experiencing recurrence and complications like vocal cord paralysis and impaired finger sensation.
      Endocrinology of Transgender Medicine

      research Endocrinology of Transgender Medicine

      166 citations , October 2018 in “Endocrine Reviews”
      This review discusses the effects of hormonal treatments on the physical and mental health of transgender individuals, reporting significant reductions in mental health issues following treatment, but calls for more research on long-term and nonbinary outcomes.