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Damaged hair follicles make mice more prone to skin inflammation and skin cancer after UV exposure.

Finasteride helps reduce blood vessel growth in diabetic rat kidneys.

Blocking EGFR in skin cells doesn't majorly increase inflammation markers.

Carbamates may help treat androgen-dependent conditions by changing how certain lipid enzymes are produced.

Low-level laser therapy seems to promote hair growth but requires more research to confirm its effectiveness.

Controlled delivery of specific RNA and IL-4 restored hair growth in mice with autoimmune alopecia.

OsPHR2 gene causes excessive phosphate in rice shoots, affecting plant growth and root development.

The system allows precise control of gene expression in mouse skin, useful for studying skin biology.

Researchers created a mouse with the same mutation as humans with trichothiodystrophy, showing similar symptoms and confirming the condition is due to defects in DNA repair and gene activity.

ERULUS controls root hair growth by regulating cell wall composition and pectin activity.

Edar signaling is crucial for controlling hair growth and regression.

ICAM-1 helps regulate hair growth cycles and skin remodeling.

Clim proteins are essential for maintaining healthy corneas and hair follicles.

Human hair follicle stem cells can be turned into red blood cells.

The MAGE3 hypothesis for alopecia areata did not lead to a significant breakthrough.

Cyclosporine starts hair growth faster, while minoxidil makes it last longer.

Brain-Derived Neurotrophic Factor (BDNF) slows down hair growth and promotes hair follicle regression.

Fetal wound healing changes with development, affecting inflammation and collagen, which may influence scarring.

Parthenolide promotes hair growth in mice and may influence pathways related to male pattern baldness.

Researchers developed a new way to measure gene activity in single hair follicles and found that a specific gene's activity changes with different amounts and times of treatment.

Stress-related substance P may lead to hair loss and negatively affect hair growth.

Alopecia areata involves specific T-cells, unlike androgenetic alopecia.

Basal cell carcinomas have much higher levels of Vitamin D3 receptors compared to healthy skin.

β-catenin is essential for stem cell activation and proliferation in hair follicles.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Sebocytes play a key role in controlling androgen levels in human skin.

Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.

Higher IGF-1 levels in hair follicles link to better finasteride results for hair loss.

Androgen hormones cause hair follicle scarring in hair loss, and finasteride helps reduce it.

Steroids, particularly estrogens and 5α-reductase inhibitors, affect blood vessel-related hair growth processes in hair follicle cells.