153 citations
,
November 2004 in “Current Medicinal Chemistry” This article updates a prior work on pharmacophore modeling and highlights the advances in 3D database searching technologies for drug design, without presenting new research findings.
112 citations
,
May 2019 in “Pharmacological Research” This review discusses the isolation, structure, and bioactivity of lignans and neolignans from 2016 to mid-2018, reporting no new clinical results but highlighting their potential protective properties against diseases such as cancer and neurodegeneration.
72 citations
,
November 2015 in “Multiple Sclerosis and Related Disorders” This study concluded that teriflunomide has a consistent and manageable safety profile, with common mild-to-moderate adverse events and no new safety concerns identified over up to 12 years of treatment.
39 citations
,
November 2017 in “Journal of The American Academy of Dermatology” This review presents standardized methods for assessing and tracking hair loss in alopecia areata but reports no clinical results, with the authors noting time limitations in clinical practice.
3 citations
,
January 2019 in “Elsevier eBooks” This article discusses the importance of interpreting laboratory data and performing physical assessments to support pharmacists in clinical decision-making and patient consultations, but reports no new empirical findings.
3 citations
,
July 2015 in “Australasian Journal of Dermatology” This letter discusses a case of iododerma in pregnancy linked to iodinated multivitamin use, but reports no new clinical findings.
2 citations
,
May 2024 in “The World Journal of Men s Health” This cohort study using real-world data found no significant difference in the risk of developing prostate cancer between finasteride and dutasteride among patients with benign prostatic hyperplasia, despite previous suggestions that dutasteride might be more effective.
1 citations
,
September 2025 in “PLoS ONE” This study identified numerous drugs with potential to trigger vitiligo, cautioning that these pharmacovigilance findings need further validation and that patients on these medications should be monitored for vitiligo development.
1 citations
,
September 2024 in “arXiv (Cornell University)” This study reviews methods to ensure the reliability of machine learning models in medical imaging, focusing on bias detection, data drift assessment, and accuracy estimation without ground truth labels to enhance integration into clinical settings.
February 2026 in “Frontiers in Immunology” In this study analyzing FDA data, researchers found that tralokinumab was associated with higher reports of conjunctivitis and keratitis compared to dupilumab, while dupilumab had more frequent injection site reactions, highlighting potential risks for clinical monitoring in atopic dermatitis treatments.
September 2025 in “Cureus” In this case report, the researchers documented a rare instance of plica neuropathica, characterized by matted and twisted hair, occurring alongside diffuse alopecia, marking the first such documented association and emphasizing its diagnostic challenges in identifying causes of alopecia.
September 2023 in “Ain Shams medical journal” In this study conducted among secondary school girls in Minia, Upper Egypt, researchers reported a traction alopecia prevalence of 31%, suggesting a significant occurrence of this potentially reversible hair loss due to tight hairstyles.
November 2017 in “Journal of Surgical Academia” This case report describes a woman with systemic lupus erythematosus who developed non-progressive visual field defects after hypertensive retinopathy, with cotton wool spots indicating retinal nerve fiber microinfarctions.
April 2012 in “The Journal of Urology” This meta-analysis reported that dietary intake of omega-3 or omega-6 fatty acids does not significantly impact prostate cancer risk.
August 2020 in “Research Square (Research Square)” This study found that an age-adjusted Charlson comorbidity index of four or more strongly predicts mortality in South Korean COVID-19 patients, highlighting the impact of comorbidity burden and older age on disease severity.
December 2024 in “International Journal of experimental research and review” In this study, the integration of obesity-related features and machine learning techniques significantly enhanced cardiovascular disease detection, with the XGBoost classifier achieving a 74% accuracy rate and improved metrics compared to other models.
120 citations
,
April 2009 in “Food Chemistry” This review examines the pharmacological evidence and bioactive compounds in Hibiscus plants, supporting their potential importance for developing treatments for chronic and degenerative diseases, though more research is needed.
67 citations
,
January 2007 in “Environmental health perspectives” This case report highlights that a woman experienced arsenic toxicosis from kelp supplements, manifesting as alopecia and memory loss, which resolved after stopping the supplements.
64 citations
,
June 2020 in “PLoS ONE” This study found that red light exposure significantly enhanced the growth, phytochemical content, and therapeutic potential of Eclipta alba callus cultures compared to other multispectral light exposures.
35 citations
,
August 2004 in “Epilepsy & behavior” In this study, divalproex sodium extended-release was found to be more tolerable and preferred by patients compared to the delayed-release formulation, with improved seizure control and psychiatric symptom relief.
23 citations
,
February 2015 in “International Journal of Molecular Sciences” This study found that colchicine treatment significantly reduced hair fiber elongation in cultured hair follicles and altered protein expression and activity in dermal papilla cells, suggesting a role for the ubiquitin-proteasome system in its effects.
14 citations
,
November 2014 in “European journal of medicinal chemistry” This study identified 30 new compounds with significant androgen receptor binding affinity through a combination of virtual screening and in vitro testing.
5 citations
,
May 2021 in “BMC surgery” This report of a rare case describes cutis verticis gyrate secondary to cerebriform intradermal nevus, emphasizing individualized treatment plans based on patient preference and condition severity.
April 2026 in “Frontiers in Pharmacology” This study revealed significant signals of drug-related cognitive disorders in several medications that lack relevant FDA label warnings, suggesting a need for increased clinical awareness and potential label updates.
February 2026 in “Cureus” This case report highlights that alopecia areata can mimic syphilitic alopecia in patients with recent or active syphilis, emphasizing the importance of trichoscopy in accurately diagnosing alopecia types and preventing misdiagnosis.
January 2026 in “Frontiers in Public Health” This study observed distinct post-marketing safety signal patterns for baricitinib and tofacitinib in adult AA, influenced by their differing regulatory uses and real-world contexts, and emphasizes the need for future studies to validate these findings.
November 2025 in “Frontiers of Agricultural Science and Engineering” This study observed that rhizobacterial strain RT3 significantly improved drought tolerance in lettuce by increasing survival rates and fresh biomass after rewatering, with metabolites such as proline and glycine enhancing stress resilience.
June 2018 in “Journal of Clinical Periodontology” Finasteride can cause gum swelling and bleeding, but stopping the drug helps recovery.
1 citations
,
February 2024 in “npj digital medicine” This study developed a deep-learning model using unannotated dermatology images from online forums, achieving 49.64% accuracy in classifying 22 skin diseases and 61.76% accuracy in detecting monkeypox, highlighting the potential of these images for skin disease diagnostics in China.
2 citations
,
May 2020 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” This study identified different skin disease profiles in primary versus secondary care in Florianopolis from 2016 to 2017, highlighting the primary care role in managing less complex conditions and referring complex cases for specialized dermatology care.