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    Glossary Sebum Production

    process where skin glands release oil to protect skin

    Sebum production, also known as sebum secretion or oil production, is the process by which sebaceous glands in the skin produce and release an oily substance called sebum. This natural oil helps to lubricate and protect the skin and hair, maintaining moisture and providing a barrier against external contaminants. Overproduction of sebum can lead to oily skin and contribute to conditions like acne, while underproduction can result in dry, flaky skin.

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    1. Sebum Production Springer eBooks · 2016 · 1 citations
    2. Adiponectin Signaling Regulates Lipid Production in Human Sebocytes PLoS ONE · 2017 · 32 citations
    3. Ozenoxacin suppresses sebum production by inhibiting mTORC1 activation in differentiated hamster sebocytes The Journal of Dermatology · 2024 · 6 citations
    4. Normal Fur Development and Sebum Production Depends on Fatty Acid 2-Hydroxylase Expression in Sebaceous Glands 2011 · 40 citations
    5. 696 MEK and BRAF inhibitors augment the production and accumulation of sebum in hamster sebocytes Journal of Investigative Dermatology · 2016
    6. 548 Deletion of Myelin Protein Zero-like 3 increases sebaceous gland size and sebocyte proliferation but reduces skin adipose depots: Can MPZL3 inhibition promote excessive loss of lipids via sebum hypersecretion? Journal of Investigative Dermatology · 2022
    7. Acetyl-CoA synthesis in the skin is a key determinant of systemic lipid homeostasis Cell Reports · 2025 · 5 citations
    8. 0952 Spatial transcriptomics reveal compartmentalized dysregulation of lipid metabolism in acne vulgaris Journal of Investigative Dermatology · 2025
    9. Refatting rate of human hair lipids after exposure to selenium disulphide detergents International Journal of Cosmetic Science · 1983 · 2 citations
    10. 1302 Disturbed sebum and microbiome composition in sensitive scalp Journal of Investigative Dermatology · 2018
    11. 1329 Transglutaminase 2 deficiency leads to lipid accumulation and reduced autophagy in SZ95 sebocytes 2023
    12. Re: Effect of Testosterone Supplementation With and Without a Dual 5α-Reductase Inhibitor on Fat-Free Mass in Men with Suppressed Testosterone Production: A Randomized Controlled Trial The Journal of Urology · 2012
    13. ANTI-ACNE ACTIVITY OF LIPIDO-STEROLIC EXTRACT OF SERENOA REPENS AND HYDRO-ALCOHOLIC EXTRACT OF GLYCYRRHIZA GLABRA IN SYRIAN HAMSTER EAR MODEL Zenodo (CERN European Organization for Nuclear Research) · 2017
    14. Formulation and Evaluation of Herbal Hair Serum Gel Zenodo (CERN European Organization for Nuclear Research) · 2026
    15. Inhibition of Insulin-Like Growth Factor-1–Induced Sebum Production by Bilobetin in Cultured Human Sebocytes Annals of Dermatology · 2019 · 8 citations
    16. Autophagy protects murine preputial glands against premature aging, and controls their sebum phospholipid and pheromone profile Autophagy · 2021 · 6 citations
    17. Autophagy protects murine preputial glands against premature aging, and controls their sebum phospholipid and pheromone profile Figshare · 2022
    18. 557 A peptide derivative with known anti-wrinkle properties was identified as potent dipeptiylpeptidase-4 inhibitor Journal of Investigative Dermatology · 2016
    19. Acne and sebaceous gland function Clinics in dermatology · 2004 · 463 citations
    20. New Pharmaceutical Concepts for Sebaceous Gland Diseases: Implementing Today’s Pre-Clinical Data into Tomorrow’s Daily Clinical Practice Current pharmaceutical biotechnology · 2012 · 16 citations
    21. Stratum corneum dysfunction in dandruff International Journal of Cosmetic Science · 2012 · 93 citations
    22. Structure and Function of the Skin Elsevier eBooks · 2009 · 6 citations
    23. Isotretinoin Informa Healthcare eBooks · 2011 · 1 citations
    24. Current concepts in the pathogenesis and treatment of acne Journal of Oral and Maxillofacial Surgery · 1998 · 8 citations
    25. Comparative studies of the ultrastructure of the sebaceous gland Tissue and Cell · 1985 · 40 citations
    26. 녹차추출물이 인체 피지선세포주에서 지질 생성에 미치는 효과 동의생리병리학회지 = Journal of physiology & pathology in Korean Medicine · 2011
    27. Greasy hair against obesity Signal transduction and targeted therapy · 2021
    28. EEMCO Guidance for the in vivo Assessment of Skin Greasiness Skin Pharmacology and Physiology · 2000 · 137 citations
    29. Endogenous retinoids in the hair follicle and sebaceous gland Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · 2011 · 50 citations
    30. Aging in the sebaceous gland Frontiers in Cell and Developmental Biology · 2022 · 36 citations