January 2025 in “Clinical and Experimental Optometry” This study found that men with androgenetic alopecia had significantly higher rates of dry eye symptoms and meibomian gland dysfunction compared to healthy controls, suggesting a potential link between the condition and these ocular issues.
3 citations
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May 2025 in “Frontiers in Pharmacology” This study identified known and potential novel adverse events, such as squamous cell carcinoma and dehydration, for vismodegib, underlining the importance of monitoring especially in the first two months of treatment.
January 2024 in “Frontiers in Bioengineering and Biotechnology” In this mouse study, researchers found that nanoparticles loaded with umbilical cord-derived stem cell membranes and minoxidil enhanced hair growth by improving drug solubility and transdermal delivery, increasing VEGF, IGF-1, MKI67, and CTNNB protein levels in skin tissue compared to regular minoxidil.
10 citations
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January 2023 in “Journal of the European Academy of Dermatology and Venereology” This review highlights the significant negative impact of alopecia areata on quality of life, mental health, and work, calling for individualized approaches and effective treatments to mitigate these effects.
5 citations
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December 2023 in “Materials” This review paper highlights the development and application of organic and biogenic nanocarriers for delivering bioactives, focusing on eco-friendly and sustainable nanotechnology strategies while addressing challenges like toxicity and paving the way for future innovations in green solution approaches.
August 2025 in “Frontiers in Endocrinology” This study examined postmenopausal hyperandrogenism related to ovarian disease and found that specific biochemical markers can help differentiate between tumorous and non-tumorous cases, with a good level of sensitivity and specificity, supporting surgical intervention for resolution.
May 2025 in “Journal of Nanobiotechnology” This study reported that an ATRA-loaded nanostructured lipid carrier gel (ATRA-NLC-Gel) improved symptoms of alopecia areata in mice by enhancing transdermal drug delivery, reducing skin irritation, and promoting hair regrowth through targeted follicle enrichment and pathway activation.
November 2022 in “Journal of Nanobiotechnology” In this study, researchers used a new method with platelet-rich plasma-loaded microcarriers to enhance dermal papilla cell activity and hair follicle regeneration, achieving significant hair and vessel growth in a mouse model compared to control groups.
16 citations
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January 2021 in “Frontiers in veterinary science” This study found no significant difference in hair cortisol concentrations, a chronic stress indicator, between sows in farrowing crates and those in loose-housing systems.
In this preclinical study, PA-011 derived from Periplaneta americana showed significant hair regrowth effects in androgenetic alopecia mouse models by inhibiting inflammation and oxidative stress, activating hair follicle stem cell proliferation, and normalizing skin microbiota, suggesting promise as an AGA treatment.
May 2025 in “Antioxidants” This review highlights how natural products with antioxidant properties can modulate the Wnt signaling pathway, potentially influencing various pathological conditions such as cancer, stroke, and regenerative medicine. It also addresses controversies in the compounds' mechanisms across different models and suggests research directions for future studies.
5 citations
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May 2024 in “Journal of Allergy and Clinical Immunology Global” In this case study, a 29-year-old male with severe atopic dermatitis and alopecia universalis experienced an excellent response to treatment with upadacitinib, indicating it may be a promising option for similar patients.
March 2024 in “Skin research and technology” This study found that CRP levels were elevated in alopecia areata patients, with an inverse linear association between serum vitamin D and CRP levels specifically noted in ophiasis AA.
The digital system for measuring melasma shows promise but needs more development for better accuracy and automation.
3 citations
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January 2021 in “Journal of The American Academy of Dermatology” This study observed that atopic dermatitis severity was associated with higher eosinophil counts and FLG variants, suggesting distinct endotypes that may require tailored treatment approaches.
January 2020 in “Przegla̧d dermatologiczny” This article presents a clinical approach to diagnosing and managing hirsutism from a dermatological perspective, but it reports no new clinical findings.
91 citations
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December 2006 in “Proceedings of the National Academy of Sciences” In this study, researchers found that hair follicle orientation in Fz6 −/− mice is disrupted and that hair may reorient itself over time through a self-organized process.
This review highlights that recent advancements in diagnostics and therapies, including AI-enhanced imaging, biomarker analysis, and novel treatments like low-dose oral minoxidil and JAK inhibitors, are improving the precision and customization of hair loss management.
February 2024 in “The Open dermatology journal” This systematic review reported that alopecia areata significantly impacts quality of life due to its psychological burdens, such as anxiety and depression, while emphasizing the need for increased awareness and support for affected individuals.
August 2021 in “Annals of Agricultural and Environmental Medicine” This review provides a detailed analysis of frontal fibrosing alopecia, focusing on its prevalence in postmenopausal Caucasian women, associated comorbidities, and potential autoimmune, genetic, hormonal, and environmental factors; it emphasizes the need for improved understanding to enhance diagnosis and treatment.
26 citations
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April 2024 in “Particle and Fibre Toxicology” In this study, researchers investigated the penetration and cellular responses to nanoplastics in human skin models with compromised barriers, finding that nanoplastics can penetrate the skin, accumulate in cells, and trigger inflammatory responses through specific signaling pathways.
10 citations
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August 2023 in “Advanced Science” This review discusses nitric oxide's physiological roles and the development of strategies for delivering it exogenously, without presenting new clinical results.
9 citations
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February 2025 in “Biomimetics” This study highlights the potential benefits and current limitations of robotic systems in nipple-sparing mastectomies, noting their promise in reducing surgeon fatigue but pointing out challenges such as longer operating times, high costs, and limited haptic feedback.
5 citations
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December 2021 in “Scientific Reports” In this study, researchers found that in mice, gonadal hormones and biological sex do not affect the expression of SARS-CoV-2 entry proteins ACE-2 and TMPRSS-2 in the respiratory tract, regardless of disease state.
February 2026 in “Biomedicines” This review highlights advancements in nanotechnology-based treatments for androgenetic alopecia, noting that these strategies could improve targeting and modulation of hair follicle environments compared to traditional therapies like minoxidil and finasteride, but also emphasizes challenges around safety, manufacturing, and regulation.
January 2026 in “Microorganisms” In a DNFB-induced mouse model of atopic dermatitis, this study found that both topical and oral formulations of the probiotic Bifidobacterium animalis J12 improved AD symptoms through distinct mechanisms, with topical applications reducing local inflammation and oral administration enhancing gut microbiota and reducing systemic inflammation.
May 2025 in “Journal of International Medical Research” In this study, micrografting technology was found to potentially shorten healing time compared to other grafting techniques, especially in treating burns, though results showed high heterogeneity and a risk of bias.
March 2024 in “International journal of molecular sciences” This study suggests that abnormal levels of zinc, copper, and iron in serum or hair may serve as auxiliary and prognostic tests for various skin diseases, though further research is necessary due to conflicting data.
November 2025 in “Trends in Immunotherapy” This study observed that exosomes from adipose stem cells and dermal papilla cells altered the immune environment in hair follicles, promoting hair regrowth in mouse models and human follicle cultures.
2 citations
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December 2022 in “The Journal of Dermatology” This study found that patients with hidradenitis suppurativa had significantly higher levels of cell-free DNA in their serum compared to healthy controls, suggesting its potential as a biomarker for the disease.