Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study used a multi-layer in silico framework to evaluate Korean herbal compounds for androgenetic alopecia, identifying Biochanin A, Saponin Re, and Emodin as potential topical candidates with distinct safety and affinity profiles, although these findings remain purely computational without experimental validation.

This study evaluated Korean herbal compounds in silico and identified Biochanin A, Saponin Re, and Emodin as potential topical treatments for androgenetic alopecia, each with specific safety and efficacy considerations.

In this study, a new herbal hair oil formulation, consisting of plant-derived antifungal agents and natural stabilizers, was developed and demonstrated strong antifungal activity, skin compatibility, and additional hair health benefits in preclinical evaluations, offering a potential alternative for managing fungal scalp infections.

In this study, in silico analysis identified Saponin Re and Emodin as promising candidates for topical treatment of androgenetic alopecia, with Biochanin A having the most favorable safety profile among the tested compounds.

Higher doses of oral minoxidil can help hair growth but may have safety risks.

Higher doses of oral minoxidil can help hair growth but may have safety risks.

This study found that the SAAD-41 is a validated tool for assessing psychosocial outcomes in individuals with alopecia areata, showing strong correlations with established measures of quality of life and coping.

In this retrospective study, baricitinib and ritlecitinib showed similar effectiveness and safety over 52 weeks for treating severe alopecia areata, with non-severe adverse events more common for baricitinib, driven by weight gain.

This study found that omega-6 and saturated fatty acid-enriched diets promote weight gain and certain skin changes regardless of gut microbiota, while omega-3 diets limit adiposity and affect skin in a microbiota-dependent way in mice, highlighting a diet–microbiota–lipid relationship in skin health.

Most young patients found oral minoxidil helpful for hair loss and were willing to continue using it.

In this study, Quercetin-loaded black seed oil nanoemulsion effectively mitigated testosterone-induced testicular oxidative stress and inflammation in rats undergoing exercise and restraint stress, with improved antioxidant levels and reduced inflammatory markers compared to other treatment groups.

This study observed that upadacitinib demonstrated significant efficacy and favorable safety for treating alopecia areata over 12 months in a real-world setting, with patients having an atopic background showing better early response; no serious adverse events were reported.

This study found that a topical 5% phenytoin solution, applied twice daily for 16 weeks, significantly improved total hair count and hair density in men with androgenetic alopecia, with mild and transient side effects observed.

In this study, women with PCOS exhibited a significantly elevated low-grade inflammatory profile through salivary cytokines, with IL-1β and TNF-α demonstrating strong potential as non-invasive diagnostic markers, alongside traditional androgen measures like FAI.

This review highlights the potential of Sacituzumab Tirumotecan, an antibody-drug conjugate, in treating gynecologic cancers, with ongoing Phase III trials indicating a manageable safety profile and future results expected to shed light on its effectiveness in improving survival and response rates.

This infographic compares the safety profiles of SH‑1, a cosmetic ingredient, which showed no systemic absorption, and PP405, an investigational drug with dose-dependent systemic uptake and potential threshold breaches, highlighting differences in safety between cosmetic and investigational substances according to this report.

This study developed an SLS-free, plant-based anti-dandruff shampoo with favorable characteristics including effective antifungal properties and consumer appeal, suggesting it as a viable alternative to synthetic products.

In this study, researchers developed a plant-based, SLS-free anti-dandruff shampoo with optimal cosmetic properties and antifungal effectiveness, reporting its potential as a safe and biodegradable alternative to synthetic products.

This descriptive literature review suggests that rosemary essential oil may stimulate hair growth in androgenetic alopecia with effects similar to 2% minoxidil, yet highlights the need for more robust clinical trials to confirm these findings and assess complementary methods like scalp massage and high-frequency treatment.

This study evaluated salmon-derived exosomes combined with microneedling as a treatment for androgenetic alopecia, reporting significant improvements in hair density, follicular health, and scalp microenvironment, with no serious adverse events observed in the 20 patients after 12 weeks.

In this study, researchers analyzed adverse event reports from the FAERS database to identify safety concerns associated with ipilimumab in elderly patients, noting common issues like gastrointestinal events and new signals such as orchitis and alopecia areata, with timing influenced by body weight.

In this study, Clitoria ternatea (Sangu Poo) was noted for its potential roles in health and skincare, with lab tests showing antioxidant, antimicrobial, liver-protective, and cancer-related activities; however, human trial evidence is lacking, impacting consistent quality and progress.

This study reviews the traditional and emerging medicinal uses of Clitoria ternatea Linn., highlighting its extensive chemical composition and potential health benefits, but notes the lack of human trial evidence and the need for better testing methods to ensure consistent quality and efficacy.

This review highlights significant knowledge gaps in the safety of alopecia treatments during pregnancy, IVF, and PCOS contexts, noting that many medications lack robust safety data, and underscores the need for more targeted research to guide treatment decisions.

In this study, real-world data of 31 patients using ritlecitinib for severe alopecia areata showed that 51% achieved significant hair regrowth after one year, with no serious adverse events reported, emphasizing the importance of considering treatment duration for response.

This study highlights Clitoria ternatea's potential in modern health and skincare, noting its antioxidant, antimicrobial, and anti-inflammatory properties observed in lab tests and exploring its uses in beauty products, yet emphasizes the need for human trials to confirm benefits and ensure quality.

In this review, Clitoria ternatea Linn., a plant from the pea family, is noted for potential health benefits, including antioxidant, antimicrobial, and anti-inflammatory effects, though human trial evidence is lacking and research on consistent quality is needed for practical applications.

This study reports that among adults with severe alopecia areata taking ritlecitinib, 49% saw hair regrowth within 3 months, increasing to 82% after more than 6 months; treatment satisfaction also rose with longer duration, indicating sustained efficacy and improved quality of life over time.