41 citations
,
September 2018 in “Australasian journal of dermatology” This review suggests that oral prednisolone pulse therapy and oral inosiplex may be effective for alopecia areata, but robust evidence from randomized controlled trials is lacking, highlighting the need for better-designed future studies.
41 citations
,
July 2002 in “Clinical and Experimental Dermatology” This review evaluates hair growth measurement methods for human scalp hair, suggesting that combining highly resolutive analytical approaches with global calibrated methods is recommended for assessing hair changes in clinical settings.
40 citations
,
July 2017 in “Frontiers in Medicine” This review highlights that in children, hair loss can be attributed to diverse conditions like alopecia areata and tinea capitis, and stresses the importance of a holistic approach to diagnosis and management, including psychosocial support due to limited effective treatments.
40 citations
,
January 2016 in “PLoS ONE” The study found that exposing Arbas Cashmere goats to a short photoperiod significantly increased cashmere production by extending the anagen phase of hair follicles, with gene expression changes identified as contributing factors.
40 citations
,
December 2011 in “British Journal of Dermatology” This article reviews how chronological aging affects female scalp hair growth and suggests that multiple factors, including environmental influences, contribute to female pattern hair loss; no new clinical results are presented.
40 citations
,
August 2006 in “Current Drug Safety” This article reviews how various drugs may cause hair loss, stimulate growth, or alter hair characteristics, but reports no new clinical results; drug-induced hair loss is typically reversible.
40 citations
,
May 1999 in “Journal of The European Academy of Dermatology and Venereology” This article outlines management guidelines for androgenetic alopecia, highlighting that continued treatment with medications like finasteride or minoxidil typically halts progression and improves hair condition in most mild to moderate cases.
39 citations
,
June 2020 in “Dermatologic Therapy” In this study, individuals reported a decrease in dermatologist visits for hair and scalp conditions like telogen effluvium and alopecia areata during COVID-19 quarantine, despite increased occurrences.
39 citations
,
January 2019 in “Cells” This review discusses the molecular mechanisms of Hutchinson-Gilford progeria syndrome and evaluates current research trends, available mouse models, and prospects for developing therapies, but reports no new clinical findings.
38 citations
,
November 2013 in “Journal of The American Academy of Dermatology” This study found that higher BMI was significantly associated with more severe hair loss in men with male-pattern and early-onset androgenetic alopecia.
38 citations
,
December 2012 in “Journal of Cutaneous Pathology” This review discusses the significance of elastic tissue staining in dermatopathology, particularly for diagnosing primary elastic tissue disorders and other skin conditions, but reports no new clinical results.
38 citations
,
February 2009 in “Journal of The European Academy of Dermatology and Venereology” This study found that patients with severe vertex pattern androgenetic alopecia had significantly higher carotid intima-media thickness, suggesting an increased risk of subclinical atherosclerosis compared to other alopecia patterns and healthy controls.
38 citations
,
February 2006 in “British Journal of Clinical Pharmacology” This study found that combining data from different databases provided a more comprehensive estimate of serious adverse drug reactions in a French university hospital, highlighting the limitations of current ADR reporting methods.
38 citations
,
February 2002 in “British journal of dermatology/British journal of dermatology, Supplement” This report describes two cases of sustained hair repigmentation related to porphyria cutanea tarda, though the underlying mechanism remains unclear.
37 citations
,
June 2021 in “Journal of the European Academy of Dermatology and Venereology” This review discusses how acute exposures to environmental and internal stressors can quickly alter skin functions, leading to various dermatological symptoms, and calls for more research on these short-term effects.
37 citations
,
April 2012 in “British Journal of Dermatology” This study found that among middle-aged Korean women, those with metabolic syndrome had a higher risk of androgenetic alopecia, while no significant association was observed in men.
37 citations
,
May 2004 in “Multiple Sclerosis Journal” This article highlights adverse skin reactions due to injectable therapies for MS, noting that while generally mild, some cases can progress to serious lesions requiring medical intervention.
37 citations
,
January 2002 in “British journal of dermatology/British journal of dermatology, Supplement” This study found that procyanidin B-2 may promote hair growth by reducing expression and inhibiting translocation of PKC isozymes in murine hair epithelial cells.
37 citations
,
January 1997 in “Clinics in Dermatology” This study found that women with androgenetic alopecia and alopecia areata had significantly lower serum ferritin levels compared to women without hair loss.
36 citations
,
December 2016 in “Journal of The American Academy of Dermatology” In this study, researchers evaluated the hair pull test and found that normal values should be reduced to two hairs or fewer, with no significant impact from hair washing, brushing, or lifestyle factors such as hair texture and medication use.
35 citations
,
November 2020 in “Dermatologic Therapy” This case series reports telogen effluvium in three patients following severe Sars-Cov-2 infection and suggests a potential association that merits further investigation.
35 citations
,
January 2014 in “Postepy Dermatologii I Alergologii” This study found that increased dihydrotestosterone levels were observed in both androgenetic alopecia patients and controls, suggesting that follicle sensitivity to DHT may be more critical than DHT levels for alopecia development.
35 citations
,
January 2014 in “BioMed Research International” This review examines the epidemiology, pathogenesis, clinical manifestations, and diagnosis of female pattern hair loss and reports no new results.
35 citations
,
January 2012 in “The Journal of Sexual Medicine” This review examines various androgen deprivation therapy methods for advanced prostate cancer, highlighting benefits and potential cardiovascular and sexual adverse effects, but reports no new clinical results.
35 citations
,
March 2011 in “International Journal of Dermatology” This study concluded that patients with metabolic syndrome, regardless of androgenetic alopecia presence, were more insulin resistant than those with only androgenetic alopecia or healthy controls, indicating no true association between alopecia and insulin resistance.
35 citations
,
March 2007 in “Skin Research and Technology” In this study, researchers developed a non-invasive method to distinguish exogen hair from telogen hair on the human scalp, finding that normal exogen hair levels are generally less than seven hairs per cm².
34 citations
,
January 2014 in “Indian Dermatology Online Journal” This study supports evaluating metabolic syndrome and insulin resistance in young males with advanced androgenic alopecia to potentially reduce future cardiovascular and type 2 diabetes risks.
34 citations
,
March 2001 in “Cleveland Clinic Journal of Medicine” This article reviews the triggers, diagnosis, and management of telogen effluvium in men and women, emphasizing the role of patient education and reassurance, but presents no new clinical findings.
33 citations
,
January 2018 in “The International Journal of Developmental Biology” This review discusses the dual role of cellular senescence in ageing and tissue repair and suggests potential therapeutic applications, with no new experimental results reported.
33 citations
,
January 2011 in “Elsevier eBooks” This article reviews the complexity and diverse manifestations of systemic lupus erythematosus, highlighting potential genetic, hormonal, and environmental factors in its pathogenesis without presenting new clinical findings.