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Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Testosterone therapy improves physical function, strength, and body composition in older men with low testosterone levels.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

A mother's diet at conception can cause lasting genetic changes in her child.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.

African spiny mice can regenerate skin, hair, and cartilage, but not muscle, and their unique abilities could be useful for regenerative medicine.

Testosterone therapy increases bone density in older men with low testosterone levels.

People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.

Polycystic ovary syndrome costs the U.S. over $4 billion a year, mainly from treating related health issues.

The guidelines suggest lifestyle changes, diet adjustments, and personalized medication to manage dyslipidemia and reduce heart disease risk.

DNA profiling in forensics has improved, but predicting physical traits and ancestry from DNA has limitations and requires ethical consideration.

Corticosteroids, especially prednisone, improve short-term muscle strength in Duchenne muscular dystrophy but have manageable side effects.

The bulletin provides guidelines for diagnosing and managing PCOS, suggesting weight loss, hormonal contraceptives, and diabetes screening, with clomiphene for infertility and various treatments for excess hair.

Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

Childhood obesity is rising globally due to various factors, and early prevention and healthy lifestyle changes are crucial.

Basal cell carcinoma mostly starts from cells in the upper skin layers, not hair follicle stem cells.

Human skin can make serotonin and melatonin, which help protect and maintain it.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

The study found that in Latin America, ancestry varies by location, influences physical traits, and affects how people perceive their own heritage.

Super-enhancers controlled by pioneer factors like SOX9 are crucial for stem cell adaptability and identity.

β-catenin in the dermal papilla is crucial for normal hair growth and repair.

Hair regeneration needs dynamic cell behavior and mesenchyme presence for stem cell activation.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

TRPA1 is crucial for mechanical sensitivity in skin sensory neurons.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.