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    Glossary Quiescent State

    period when cells are inactive or not dividing

    The quiescent state, also known as the resting state, refers to a period during which cells or tissues are inactive or not undergoing active growth and division. In the context of hair biology, this is often associated with the telogen phase of the hair growth cycle, where hair follicles are not actively producing new hair but are instead in a state of rest before shedding and eventually re-entering the growth phase.

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    1. The Stem Cell Quiescence and Niche Signaling is Disturbed in the Hair Follicle of the Hairpoor Mouse, an MUHH Model Mouse. Research Square (Research Square) · 2021
    2. The incidental pore: Ca<sub>V</sub>1.2 and stem cell activation in quiescent hair follicles Genes & development · 2013 · 3 citations
    3. Integrative Whole-Transcriptome Sequencing Analysis of Skin Tissues with Different Coat Types in Cashmere Goats Across Stages of Hair Follicle Development 2026
    4. The transcriptional landscape of seasonal coat colour moult in the snowshoe hare Molecular ecology · 2017 · 28 citations
    5. Influence of Hair Growth Cycle on Lipid Composition of Mouse Epidermis and Dermis. Experimental Biology and Medicine · 1960 · 6 citations
    6. Keratin 15 Promoter Targets Putative Epithelial Stem Cells in the Hair Follicle Bulge Journal of Investigative Dermatology · 2003 · 387 citations
    7. Adenovirus-Mediated Wnt5a Expression Inhibits the Telogen-To-Anagen Transition of Hair Follicles in Mice International journal of medical sciences · 2013 · 19 citations
    8. Identification of Telogen Markers Underscores that Telogen Is Far from a Quiescent Hair Cycle Phase 2011 · 21 citations
    9. Epidermal stem cell diversity and quiescence EMBO molecular medicine · 2009 · 168 citations
    10. A Subset of TREM2+ Dermal Macrophages Secretes Oncostatin M to Maintain Hair Follicle Stem Cell Quiescence and Inhibit Hair Growth Cell Stem Cell · 2019 · 101 citations
    11. Smad1 and 5 but Not Smad8 Establish Stem Cell Quiescence Which Is Critical to Transform the Premature Hair Follicle During Morphogenesis Toward the Postnatal State Stem Cells · 2013 · 31 citations
    12. Outcomes of Fat Grafting in the Active Versus Quiescent Phase of Localized Scleroderma Plastic Surgery · 2023
    13. Investigation of Transcriptional Gene Profiling in Normal Murine Hair Follicular Substructures Using Next-Generation Sequencing to Provide Potential Insights into Skin Disease Cell Transplantation · 2016 · 1 citations
    14. Faculty Opinions recommendation of Hair cycle resting phase is regulated by cyclic epithelial FGF18 signaling. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · 2012
    15. From neural crest cells to melanocytes: cellular plasticity during development and beyond Cellular and Molecular Life Sciences · 2019 · 66 citations
    16. Physiological Regeneration of Skin Appendages and Implications for Regenerative Medicine Physiology · 2012 · 60 citations
    17. A case report of lupus panniculitis-induced facial lipoatrophy successfully treated with injectable hyaluronic acid SAGE Open Medical Case Reports · 2024
    18. The Mesenchymal Niche of the Hair Follicle Induces Regeneration by Releasing Primed Progenitors from Inhibitory Effects of Quiescent Stem Cells Cell Reports · 2018 · 35 citations
    19. H2AK119ub dynamics control hair follicle stem cell quiescence Nature Communications · 2025 · 2 citations
    20. Transcriptome Dynamics Reveal Stage-Specific and Melatonin-Triggered Gene Expression Patterns During The Cashmere Growth Cycle in Capra Hircus Research Square (Research Square) · 2021
    21. Calcineurin/Nfatc1 signaling links skin stem cell quiescence to hormonal signaling during pregnancy and lactation Genes & Development · 2014 · 40 citations
    22. Dissecting the boundary of quiescence and activation of murine melanocyte stem cells in the hair follicle niche npj Regenerative Medicine · 2026
    23. The stem cell quiescence and niche signaling is disturbed in the hair follicle of the hairpoor mouse, an MUHH model mouse Stem cell research & therapy · 2022 · 2 citations
    24. Resting no more: re‐defining telogen, the maintenance stage of the hair growth cycle Biological Reviews · 2014 · 120 citations
    25. Immunization by Application of DNA Vaccine onto a Skin Area Wherein the Hair Follicles Have Been Induced into Anagen-onset Stage Molecular therapy · 2007 · 20 citations
    26. Stem Cells on Alert: Priming Quiescent Stem Cells after Remote Injury Cell stem cell · 2014 · 13 citations
    27. Molecular heterogeneity of quiescent melanocyte stem cells revealed by single‐cell RNA‐sequencing Pigment cell & melanoma research · 2024
    28. TGF-β Family Signaling in Epithelial Differentiation and Epithelial–Mesenchymal Transition Cold Spring Harbor Perspectives in Biology · 2017 · 82 citations
    29. Regulation of adult stem cell quiescence and its functions in the maintenance of tissue integrity Nature Reviews Molecular Cell Biology · 2023 · 200 citations
    30. The Majority of Multipotent Epidermal Stem Cells Do Not Protect Their Genome by Asymmetrical Chromosome Segregation Stem Cells · 2008 · 61 citations