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research Pharmacophore Modeling and Three Dimensional Database Searching for Drug Design Using Catalyst: Recent Advances
This article updates a prior work on pharmacophore modeling and highlights the advances in 3D database searching technologies for drug design, without presenting new research findings.
research In-Depth Exploration of Chemical Constituents from Justicia procumbens L. Through UHPLC-Q-Exactive Orbitrap Mass Spectrometry
In this study, researchers using advanced chromatography and mass spectrometry techniques tentatively identified 132 chemical compounds in Justicia procumbens, including 54 lignans and 77 compounds reported for the first time, which may aid in pharmacological research and quality control of the plant.
research Pertinence d’une chimioprévention à partir de l’étude PCPT
This article discusses the potential of finasteride as a chemopreventive agent for prostate cancer and highlights unresolved issues, but it reports no new research findings.
research References
This abstract compiles a list of references on pharmaceutical and chemical engineering topics without presenting any new research findings.
research Finasteride 98319‐26‐7
research Optimizing finasteride chemoprevention
research Cancer Chemotherapy: an Introduction
This paper reviews the principles and challenges of cytotoxic drug therapy in cancer treatment, including effects on normal tissues, drug resistance, administration methods, and the clinical role of chemotherapy, without reporting new experimental results.
research Data-driven strategies for drug repurposing: insights, recommendations, and case studies
In this study, the researchers performed a comparative analysis of drug-target interaction data from multiple databases to refine drug repurposing strategies, revealing potential associations between drug characteristics and therapeutic groups, and predicting repositioning opportunities for FDA-approved drugs across major cancer types.
research Hair
research Annual Meeting Symposia JPS Satellite Symposium Company Organized Symposia Young Scientist Symposia Joint Symposium with the Japanese Medical Science Federation Joint Symposium with the Physiological Society of Japan Joint Symposium with the Japanese Society of Toxicology Symposia
This discussion reviews the shift in pharmaceutical strategy towards evidence-based and structure-guided drug development, highlighting ongoing challenges and efforts in computer-aided drug design without presenting new clinical results.
research Caractérisation physique et chimique des substances à activité thérapeutique : application aux études de profil de stabilité et de préformulation
In this study, the stability properties of various active pharmaceutical ingredients (APIs) were characterized, revealing how factors like pressure and water sensitivity influence their intrinsic stability and potential degradation.
research Chemoprevention – History and general principles
Cancer prevention has progressed with successful drugs and vaccines, but challenges remain in understanding genetic changes and improving strategies.
research Abstract SS02-02: Chemoprevention: Poised for Success
This article reviews pivotal trials and recent findings in chemoprevention for breast, prostate, and colorectal cancers, emphasizing its potential and the importance of further research, public education, and partnerships, but reports no new results.
research Advancing PROTAC therapeutics through chemistry-guided design of smart delivery systems
This review highlights how integrating medicinal chemistry with delivery science could transform the limitations of PROTACs—such as poor solubility and low cell permeability—into strengths, potentially advancing these compounds from experimental stages to clinical applications by optimizing their delivery and enhancing therapeutic efficacy.
research Biochemistry of skin in health and disease
This monograph reviews the significant progress in skin biochemistry research over eight to ten years, highlighting key areas and identifying gaps in interpretation.
research Chemical Fingerprint and Quantitative Analysis for the Quality Evaluation of Platycladi cacumen by Ultra-performance Liquid Chromatography Coupled with Hierarchical Cluster Analysis
This study established a rapid and accurate ultra-performance liquid chromatographic method for chemical fingerprinting and analyzing Platycladi cacumen, effectively distinguishing batches based on geographical and climatic conditions.
research DRUGS OF ABUSE | Hair
research Diagnostic Comparison: SH‑1 Molecule vs PP405 — Safety Profiles in Hair Science
This infographic compares the safety profiles of SH‑1, a cosmetic ingredient, which showed no systemic absorption, and PP405, an investigational drug with dose-dependent systemic uptake and potential threshold breaches, highlighting differences in safety between cosmetic and investigational substances according to this report.
research Polymorphism
This chapter discusses phase transitions in various pharmaceutical examples and does not present any new research findings.
research Optimization of finasteride nano-emulsion preparation by using chemometrics approaches (and/or Box-Behnken design and regresion model)
research Subject Index, Vol. 7,1994
research Finasteride
research Finasteride
research Valency based novel quantitative structure property relationship (QSPR) approach for predicting physical properties of polycyclic chemical compounds
This study reports that the new neighborhood face index (NFI) demonstrates a remarkably high correlation with the physiochemical properties of benzenoid hydrocarbons, highlighting its potential as a predictive tool.
research The antiandrogen cyproterone acetate: discovery, chemistry, basic pharmacology, clinical use and tool in basic research*
research Synthesis, biological evaluation and molecular docking of 4-Amino-2H-benzo[h]chromen-2-one (ABO) analogs containing the piperazine moiety
This study identified novel 4-Amino-2H-benzo[h]chromen-2-one analogs as potent androgen receptor antagonists that show strong antiproliferative activity against prostate cancer cells, suggesting them as potential lead compounds for therapy development.
research Primary Chemoprevention Still Lacks Favor with General Physicians & Patients
This research observed that both patients and primary care physicians are hesitant to fully embrace chemoprevention for cancer due to concerns over risk identification, side effects, and a lack of definitive guidance.
research Solid-Phase Microextraction and Related Techniques in Bioanalysis
This reprint reviews 14 papers on advances in solid-phase microextraction techniques for bioanalysis, reporting no new results.
research DETERMINATION OF FINASTERIDE AND RELATED COMPOUNDS BY REVERSED-PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY. I. CHOOSING THE MOBILE PHASE COMPOSITION
This article discusses using high performance liquid chromatography to optimize mobile phase composition for separating synthesis products of Finasteride, without reporting new clinical results.